INT43221

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Context Info
Confidence 0.18
First Reported 1983
Last Reported 1983
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.85

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Adcyap1) signal transduction (Adcyap1) extracellular space (Adcyap1)
extracellular region (Adcyap1)
Anatomy Link Frequency
pituitary 2
Adcyap1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 6 100.00 Very High Very High Very High
antagonist 3 99.98 Very High Very High Very High
dopamine receptor 6 93.52 High High
agonist 5 88.72 High High
Clonidine 1 81.20 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
All classical dopaminergic antagonists blocked dopamine inhibition of pituitary adenylate cyclase, pimozide (KI 1 nM) and spiperone (KI 0.8 nM) being the more potent.
Negative_regulation (blocked) of Negative_regulation (inhibition) of pituitary adenylate cyclase in pituitary associated with dopamine and antagonist
1) Confidence 0.18 Published 1983 Journal Mol. Pharmacol. Section Abstract Doc Link 6306429 Disease Relevance 0 Pain Relevance 0.85

General Comments

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