INT43282

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Context Info
Confidence 0.32
First Reported 1983
Last Reported 1996
Negated 2
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 0.61
Pain Relevance 2.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Gcg) extracellular region (Gcg) cytoplasm (Gcg)
Anatomy Link Frequency
plasma 1
liver 1
Gcg (Rattus norvegicus)
Pain Link Frequency Relevance Heat
lidocaine 2 99.44 Very High Very High Very High
Morphine 20 98.48 Very High Very High Very High
Opioid 1 97.32 Very High Very High Very High
Somatostatin 4 93.12 High High
anesthesia 1 91.44 High High
nMDA receptor 3 82.56 Quite High
excitatory amino acid 2 75.00 Quite High
antagonist 1 64.40 Quite High
Cholecystokinin 1 52.16 Quite High
Bile 1 51.52 Quite High
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 3 94.40 High High
Hyperglycemia 4 93.24 High High
Stress 1 91.84 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Beta-receptor stimulation seems to contribute to the glucagon but not to the insulin release after morphine.
glucagon Neg (not) Binding (contribute) of associated with morphine
1) Confidence 0.32 Published 1993 Journal Life Sci. Section Abstract Doc Link 8102765 Disease Relevance 0 Pain Relevance 1.04
Procaine treatment increased the glucagon and fluoride activation of the cyclase and the stimulation was concentration-dependent; this compound seemed to act at the G/F unit level since changes in the glucagon binding were not observed and the basal activity was not modified.
glucagon Binding (binding) of
2) Confidence 0.32 Published 1983 Journal Biochim. Biophys. Acta Section Abstract Doc Link 6309252 Disease Relevance 0 Pain Relevance 0.09
Rat liver plasma membranes were incubated either with procaine, lidocaine or tetracaine to study the binding of glucagon to receptors and the responses of adenylate cyclase to glucagon or fluoride.
glucagon Binding (binding) of in liver associated with lidocaine
3) Confidence 0.31 Published 1983 Journal Biochim. Biophys. Acta Section Abstract Doc Link 6309252 Disease Relevance 0 Pain Relevance 0.10
Morphine increased the plasma concentration of epinephrine (4-fold), norepinephrine (2-fold) and corticosterone (67%); however, no alterations in plasma insulin and glucagon were detected.
glucagon Neg (no) Binding (alterations) of in plasma associated with morphine
4) Confidence 0.23 Published 1996 Journal Brain Res. Section Abstract Doc Link 8720499 Disease Relevance 0.52 Pain Relevance 0.81
Comparison of hepatic extraction of insulin and glucagon in conscious and anesthetized dogs.
glucagon Binding (extraction) of
5) Confidence 0.03 Published 1983 Journal Endocrinology Section Title Doc Link 6337043 Disease Relevance 0.09 Pain Relevance 0.14

General Comments

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