INT43385

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Context Info
Confidence 0.58
First Reported 1983
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.49
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (C6) extracellular region (C6)
C6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 2 89.04 High High
addiction 1 88.64 High High
Opioid 1 63.68 Quite High
Pain 3 36.36 Quite Low
headache 2 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Flavivirus Infection 80 98.44 Very High Very High Very High
INFLAMMATION 3 89.04 High High
Infection 51 88.28 High High
Dengue 104 88.08 High High
Stress 2 85.40 High High
Disease 23 85.04 High High
Injury 14 82.92 Quite High
Thalassemia 1 82.08 Quite High
Hemolytic Anemia 2 81.48 Quite High
Sickle Cell Anemia 8 80.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have characterized the binding of 125I-labeled human beta-endorphin (125I-beta H-endorphin) to sites present on the terminal fluid-phase complex of human complement, consisting of complement components C5b, C6, C7, C8, C9, and the S-protein (SC5b-9 complex).
Gene_expression (consisting) of C6
1) Confidence 0.58 Published 1983 Journal J. Biol. Chem. Section Abstract Doc Link 6313649 Disease Relevance 0 Pain Relevance 0.11
The other surface patch is generated using the curves c6, c7, c8, c9 and c10 where the curve c6 is common to both surface patches.
Gene_expression (using) of c6
2) Confidence 0.25 Published 2005 Journal Theor Biol Med Model Section Body Doc Link PMC1198260 Disease Relevance 0.43 Pain Relevance 0
In a pioneering study, Bokisch et al. [3] measured the levels of nine complement factors (C1q, C1s, C2, C3, C4, C5, C6, C8 and factor B) in serum samples of DHF patients (grades I to IV).
Gene_expression (levels) of C6 associated with flavivirus infection
3) Confidence 0.18 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2728508 Disease Relevance 1.43 Pain Relevance 0
This may explain why these bacteria accumulated lethal complement activation products [C3, C6 and C5b-9 (MAC)] on their surfaces (Fig. 7).
Gene_expression (products) of C6
4) Confidence 0.13 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2958145 Disease Relevance 0 Pain Relevance 0
The most prevalent polymorphic variants of the HbB gene consist of the normal gene (HbA) in which SNPs in the same amino acid position give rise to either the sickle haemoglobin S, (HbS, Glu to Val at c6 (E6V)) or the common west-African haemoglobin C (HbC, Glu to Lys at c6 (E6K)).
Gene_expression (consist) of c6
5) Confidence 0.13 Published 2005 Journal Malar J Section Body Doc Link PMC1326224 Disease Relevance 0.64 Pain Relevance 0.04

General Comments

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