INT43540

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Context Info
Confidence 0.01
First Reported 1984
Last Reported 1984
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 1.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transferase activity, transferring glycosyl groups (fut10) Golgi apparatus (fut10)
Anatomy Link Frequency
brain 1
egg 1
fut10 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
sodium channel 9 98.84 Very High Very High Very High
tetrodotoxin 12 83.36 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data indicate that the alpha, beta 1, and beta 2 subunits of the sodium channel are sufficient for reconstitution of both selective, veratridine-stimulated ion transport and 125I-LqTx binding.
LqTx Binding (binding) of associated with sodium channel
1) Confidence 0.01 Published 1984 Journal J. Biol. Chem. Section Abstract Doc Link 6319406 Disease Relevance 0 Pain Relevance 0.23
Purified sodium channels reconstituted in egg phosphatidylcholine vesicles do not bind 125I-scorpion toxin (125I-LqTx).
LqTx Neg (not) Binding (bind) of in egg associated with sodium channel
2) Confidence 0.01 Published 1984 Journal J. Biol. Chem. Section Abstract Doc Link 6319406 Disease Relevance 0 Pain Relevance 0.41
In contrast, when incorporated into vesicles containing rat brain lipids, 76% of the Na+ channels bound 125I-LqTx with an average KD of 80 nM.
LqTx Binding (bound) of in brain
3) Confidence 0.01 Published 1984 Journal J. Biol. Chem. Section Abstract Doc Link 6319406 Disease Relevance 0 Pain Relevance 0.39

General Comments

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