INT43584

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Context Info
Confidence 0.35
First Reported 1983
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.10
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (VEGFC) signal transduction (VEGFC) extracellular space (VEGFC)
extracellular region (VEGFC)
Anatomy Link Frequency
vessels 1
placenta 1
VEGFC (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 1 83.72 Quite High
chemokine 3 80.12 Quite High
cytokine 6 79.64 Quite High
opiate 1 75.00 Quite High
Clonidine 1 71.60 Quite High
imagery 12 5.00 Very Low Very Low Very Low
Inflammation 9 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
COX-2 inhibitor 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Eclampsia 5 99.36 Very High Very High Very High
Fibromyalgia 2 95.04 Very High Very High Very High
Cancer 74 92.04 High High
Hypertension 1 75.00 Quite High
Stress 2 72.80 Quite High
Hypoxia 2 65.04 Quite High
Hematological Disease 11 39.76 Quite Low
Metastasis 61 5.00 Very Low Very Low Very Low
Breast Cancer 16 5.00 Very Low Very Low Very Low
INFLAMMATION 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
VEGF-C interacts with VEGF receptors on endothelial cells to stimulate angiogenesis and lymphangiogenesis when existing vessels are destabilized.
VEGF-C Binding (interacts) of in vessels
1) Confidence 0.35 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2529338 Disease Relevance 0.76 Pain Relevance 0.08
Soluble Flt-1 binds to circulating free vascular endothelial growth factor and placenta growth factor and this is associated with endothelial dysfunction.
vascular endothelial growth factor Binding (binds) of in placenta
2) Confidence 0.20 Published 2009 Journal Clin. Exp. Pharmacol. Physiol. Section Abstract Doc Link 19215236 Disease Relevance 0.34 Pain Relevance 0.07
The high affinity site for DHM and the low of DADLE are the more easily displaced by B-EP, but with different affinities.
DHM Binding (displaced) of
3) Confidence 0.04 Published 1983 Journal Life Sci. Section Abstract Doc Link 6319877 Disease Relevance 0 Pain Relevance 0.16

General Comments

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