INT43587

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Context Info
Confidence 0.00
First Reported 1983
Last Reported 1983
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Pah) plasma membrane (OPRD1) cytoplasm (OPRD1)
signal transducer activity (OPRD1)
OPRD1 (Homo sapiens)
Pah (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 1 99.40 Very High Very High Very High
Potency 3 98.42 Very High Very High Very High
Dynorphin 1 81.36 Quite High
Opioid 2 75.00 Quite High
opioid receptor 1 58.32 Quite High
Disease Link Frequency Relevance Heat
Reprotox - General 2 1 83.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The observation that Phe(pNO2) substitution in position 3 of morphiceptin and dermorphin also produces a drastic potency drop indicates that the Phe3 side-chain of the latter peptides at the mu- and delta-receptor may bind to a site different from that interacting with the Phe4 side-chain of enkephalins.
delta-receptor Binding (interacting) of Phe4 associated with enkephalin and potency
1) Confidence 0.00 Published 1983 Journal Life Sci. Section Abstract Doc Link 6319885 Disease Relevance 0.08 Pain Relevance 0.43

General Comments

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