INT43796

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.06
First Reported 1984
Last Reported 1984
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (CDS1, Adra2a) endoplasmic reticulum (CDS1) plasma membrane (Adra2a)
cytoplasm (Adra2a) signal transducer activity (Adra2a) nucleotidyltransferase activity (CDS1)
Anatomy Link Frequency
brain 1
CDS1 (Homo sapiens)
Adra2a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 4 100.00 Very High Very High Very High
Neurotransmitter 2 100.00 Very High Very High Very High
antagonist 2 97.00 Very High Very High Very High
Clonidine 6 93.56 High High

|}

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CDS binds specifically to alpha 2-adrenergic receptors by competing with either alpha 2-adrenergic agonists or alpha 2-antagonists, but has no effect on the specific binding of [3H]prazosin to alpha 1-adrenergic receptors in rat brain membranes.
CDS Binding (binds) of alpha 2-adrenergic in brain associated with antagonist and agonist
1) Confidence 0.06 Published 1984 Journal FEBS Lett. Section Abstract Doc Link 6327389 Disease Relevance 0 Pain Relevance 0.43
In the course of isolation, CDS was shown to be neither the endogenous neurotransmitter (-)norepinephrine (NE) nor the guanyl nucleotide GTP which lowers the specific binding of alpha 2-agonists to the alpha 2-adrenergic receptors.
CDS Binding (binding) of alpha 2-adrenergic associated with neurotransmitter and agonist
2) Confidence 0.04 Published 1984 Journal FEBS Lett. Section Abstract Doc Link 6327389 Disease Relevance 0 Pain Relevance 0.43

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox