INT43900

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Context Info
Confidence 0.58
First Reported 1984
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 13
Total Number 14
Disease Relevance 12.00
Pain Relevance 2.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (RASA1) signal transduction (RASA1) plasma membrane (RASA1)
embryo development (RASA1) cytoplasm (RASA1)
Anatomy Link Frequency
tendon 1
RASA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 28 99.64 Very High Very High Very High
Trigeminal neuralgia 6 98.24 Very High Very High Very High
Inflammation 40 98.16 Very High Very High Very High
headache 11 98.12 Very High Very High Very High
drug abuse 285 97.04 Very High Very High Very High
cannabis 80 95.96 Very High Very High Very High
cocaine 140 95.20 Very High Very High Very High
Pain 19 95.20 Very High Very High Very High
cytokine 12 94.40 High High
diclofenac 1 88.08 High High
Disease Link Frequency Relevance Heat
Periodontitis 50 100.00 Very High Very High Very High
Arterial-venous Cerebral Malformations 17 100.00 Very High Very High Very High
Cv General 4 Under Development 11 99.64 Very High Very High Very High
Post-traumatic Stress Disorder 532 99.60 Very High Very High Very High
Brain Injury 335 99.24 Very High Very High Very High
Apoptosis 96 99.04 Very High Very High Very High
Convulsion 12 98.52 Very High Very High Very High
Neuralgia 6 98.24 Very High Very High Very High
INFLAMMATION 46 98.16 Very High Very High Very High
Headache 12 98.12 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Palpation showed the right calf to be soft; a distinct gap was found in the middle third of the Achilles tendon.
Gene_expression (found) of gap in tendon
1) Confidence 0.58 Published 2008 Journal Dtsch. Med. Wochenschr. Section Abstract Doc Link 18236349 Disease Relevance 0.38 Pain Relevance 0.13
Air contrast CT cisternography is one of the safety and convenient methods to detect the AVM and other vascular anormalies resulting in trigeminal neuralgia.
Gene_expression (detect) of AVM associated with trigeminal neuralgia and arterial-venous cerebral malformations
2) Confidence 0.52 Published 1984 Journal No To Shinkei Section Abstract Doc Link 6335663 Disease Relevance 1.99 Pain Relevance 0.79
Overlap Between Gap in Memory
Gene_expression (Overlap) of Gap
3) Confidence 0.12 Published 2010 Journal Psychol Inj Law Section Body Doc Link PMC2948674 Disease Relevance 1.49 Pain Relevance 0
Diagnosing a Gap in Memory
Gene_expression (Diagnosing) of Gap
4) Confidence 0.10 Published 2010 Journal Psychol Inj Law Section Body Doc Link PMC2948674 Disease Relevance 1.35 Pain Relevance 0
The GaP study has two stages:
Gene_expression (study) of GaP
5) Confidence 0.09 Published 2006 Journal BMC Health Serv Res Section Body Doc Link PMC1513223 Disease Relevance 0.60 Pain Relevance 0
The microsurgical technique used consisted of retrograde dissection of the AVM from the venous side in most cases.
Gene_expression (dissection) of AVM
6) Confidence 0.08 Published 2009 Journal Journal of neurosurgery. Spine Section Body Doc Link 19442003 Disease Relevance 0 Pain Relevance 0
Groups defined by global transcriptional profiles: selection and GAP criteria
Gene_expression (criteria) of GAP
7) Confidence 0.08 Published 2006 Journal PLoS ONE Section Body Doc Link PMC1762434 Disease Relevance 0.10 Pain Relevance 0.05
90%) had GAP scores ?
Gene_expression (scores) of GAP
8) Confidence 0.08 Published 2006 Journal PLoS ONE Section Body Doc Link PMC1762434 Disease Relevance 0.41 Pain Relevance 0.16
The probability of decreased or increased expression were selected as GAP ?
Gene_expression (selected) of GAP
9) Confidence 0.08 Published 2006 Journal PLoS ONE Section Body Doc Link PMC1762434 Disease Relevance 0.20 Pain Relevance 0.20
The higher frequency of Bcl-2 positivity in our GAP group indicates that delayed apoptosis can lead to inflammatory cells staying locally in periodontal tissues longer and thus secreting excessive cytokines, finally to progressive periodontal destruction.
Gene_expression (group) of GAP associated with periodontitis, inflammation, apoptosis and cytokine
10) Confidence 0.08 Published 2006 Journal Head Face Med Section Body Doc Link PMC1524725 Disease Relevance 1.85 Pain Relevance 0.20
Transcripts for which one (or more) GAP was ?
Gene_expression (was) of GAP
11) Confidence 0.07 Published 2006 Journal PLoS ONE Section Body Doc Link PMC1762434 Disease Relevance 0.09 Pain Relevance 0.04
Groups defined by toxicology: selection and GAP criteria
Gene_expression (criteria) of GAP
12) Confidence 0.07 Published 2006 Journal PLoS ONE Section Body Doc Link PMC1762434 Disease Relevance 0.16 Pain Relevance 0.16
The aim of the present study was to investigate the clinical features and known indicators of apoptosis (p53, Bcl-2, Caspase-3) in patients with generalized aggressive periodontitis (GAP)

Methods

Gene_expression (aggressive) of GAP associated with periodontitis and apoptosis
13) Confidence 0.07 Published 2006 Journal Head Face Med Section Abstract Doc Link PMC1524725 Disease Relevance 1.25 Pain Relevance 0.09
Patients with an AVM present with an SAH, neurological deficits, seizures, headaches or may be completely asymptomatic.
Gene_expression (present) of AVM associated with convulsion, headache, cva and arterial-venous cerebral malformations
14) Confidence 0.01 Published 2010 Journal Anesthesiology Research and Practice Section Body Doc Link PMC2911602 Disease Relevance 2.15 Pain Relevance 0.21

General Comments

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