INT43907

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Context Info
Confidence 0.48
First Reported 1983
Last Reported 2010
Negated 2
Speculated 0
Reported most in Abstract
Documents 28
Total Number 29
Disease Relevance 28.11
Pain Relevance 3.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CD79A)
Anatomy Link Frequency
ASC 2
plasma 1
blood 1
oesophagus 1
visceral organs 1
CD79A (Homo sapiens)
Pain Link Frequency Relevance Heat
abdominal pain 23 99.98 Very High Very High Very High
rheumatoid arthritis 17 99.98 Very High Very High Very High
cINOD 4 99.72 Very High Very High Very High
Pain 14 99.70 Very High Very High Very High
Arthritis 10 97.36 Very High Very High Very High
Inflammation 34 96.64 Very High Very High Very High
headache 12 93.32 High High
peripheral neuropathy 9 92.32 High High
backache 2 89.44 High High
cytokine 18 82.64 Quite High
Disease Link Frequency Relevance Heat
Motor Neuron Diseases 176 100.00 Very High Very High Very High
Renal Disease 22 100.00 Very High Very High Very High
Bullous Skin Disease 13 100.00 Very High Very High Very High
Skin Diseases 2 100.00 Very High Very High Very High
Hypersensitivity Vasculitis 1 100.00 Very High Very High Very High
Abdominal Pain 23 99.98 Very High Very High Very High
Rheumatoid Arthritis 17 99.98 Very High Very High Very High
Myelodysplastic Syndromes 11 99.98 Very High Very High Very High
Macroglobulinemia 10 99.98 Very High Very High Very High
Tabes Dorsalis 4 99.98 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although relapsing polychondritis is known to associate rarely with renal involvement, it is very rare to associate with IgA nephropathy.
IgA Binding (associate) of associated with relapsing polychondritis and renal disease
1) Confidence 0.48 Published 1998 Journal Nihon Rinsho Meneki Gakkai Kaishi Section Abstract Doc Link 9884550 Disease Relevance 1.10 Pain Relevance 0.09
IgA aCL was strongly associated with the outcome (nonadjusted OR 11.5 after Agresti correction).
IgA Binding (associated) of
2) Confidence 0.47 Published 2007 Journal Angiology Section Abstract Doc Link 17626983 Disease Relevance 0.81 Pain Relevance 0.12
Celiac disease is associated with IgA deficiency and it is 10-times more frequent in patients with Ig A deficiency than in the general population.35 Serum Ig A deficiency was detected in 9.1% of patients in the present study, which is higher than expected in the normal population.
IgA Binding (associated) of associated with celiac disease
3) Confidence 0.47 Published 2009 Journal Yonsei Medical Journal Section Body Doc Link PMC2768234 Disease Relevance 1.42 Pain Relevance 0.03
[Two cases of rheumatoid arthritis associated with IgA -type multiple myeloma].
IgA Binding (associated) of associated with rheumatoid arthritis and multiple myeloma
4) Confidence 0.37 Published 2000 Journal Ryumachi Section Title Doc Link 10783663 Disease Relevance 1.26 Pain Relevance 0.31
A skin biopsy revealed leukocytoclastic vasculitis with IgA deposits.
IgA Binding (vasculitis) of in skin associated with hypersensitivity vasculitis
5) Confidence 0.36 Published 1999 Journal J. Nephrol. Section Abstract Doc Link 10440519 Disease Relevance 0.47 Pain Relevance 0.10
IgA aCL and IgA anti-beta2-gpI antibodies were not associated with any known risk factors for sPAD or with arteriography changes.
IgA Neg (not) Binding (associated) of
6) Confidence 0.36 Published 2007 Journal Angiology Section Abstract Doc Link 17626983 Disease Relevance 0.68 Pain Relevance 0.09
IgA aCL and IgA anti-beta2-gpI antibodies were not associated with any known risk factors for sPAD or with arteriography changes.
IgA Neg (not) Binding (associated) of
7) Confidence 0.36 Published 2007 Journal Angiology Section Abstract Doc Link 17626983 Disease Relevance 0.67 Pain Relevance 0.09
Linear IgA dermatosis is clinically similar to dermatitis herpetiformis, but it is not associated with gluten-sensitive enteropathy as is dermatitis herpetiformis.
IgA Binding (associated) of associated with skin diseases, enteropathy and bullous skin disease
8) Confidence 0.36 Published 2002 Journal Am Fam Physician Section Abstract Doc Link 12018809 Disease Relevance 2.05 Pain Relevance 0.07
Quantitation of IgG and IgA antibodies to Yersinia is important in the diagnosis of Yersinia arthritis.
IgA Binding (Quantitation) of associated with arthritis
9) Confidence 0.36 Published 1983 Journal Clin. Exp. Rheumatol. Section Abstract Doc Link 6335856 Disease Relevance 1.22 Pain Relevance 0.45
In addition, they noted a significant association between the unfavorable karyotypes and immunoglobulin A (IgA) isotype, elevated levels of ?
IgA Binding (association) of
10) Confidence 0.36 Published 2010 Journal Core evidence Section Body Doc Link PMC2899783 Disease Relevance 0.73 Pain Relevance 0
We report here two Japanese cases of rheumatoid arthritis (RA) associated with IgA [symbol: see text]-type multiple myeloma (MM).
IgA Binding (associated) of associated with rheumatoid arthritis and multiple myeloma
11) Confidence 0.35 Published 2000 Journal Ryumachi Section Abstract Doc Link 10783663 Disease Relevance 0.94 Pain Relevance 0.26
It also interacts with IgA (CD79A; P?
IgA Binding (interacts) of
12) Confidence 0.35 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2483296 Disease Relevance 0.58 Pain Relevance 0.06
Henoch-Schönlein purpura (HSP) is a form of cutaneous small vessel vasculitis that can involve visceral organs and is associated with deposition of immunoglobulin A (IgA)-containing immune complexes.
IgA Binding (sociated w) of in visceral organs associated with purpura and increased venous pressure under development
13) Confidence 0.35 Published 2006 Journal Cutis Section Abstract Doc Link 16706241 Disease Relevance 1.38 Pain Relevance 0.08
Abdominal pain associated with IgA nephropathy.
IgA Binding (associated) of associated with abdominal pain and renal disease
14) Confidence 0.33 Published 1984 Journal Am. J. Med. Section Title Doc Link 6385695 Disease Relevance 0.75 Pain Relevance 0.38
Diagnosis is based on positivity of IgA and IgG antigliadin and endomysial antibodies and characteristic endoscopic detection of inflammation and atrophy of duodenal mucose.
IgA Binding (positivity) of associated with inflammation and frailty
15) Confidence 0.32 Published 2009 Journal Cas. Lek. Cesk. Section Abstract Doc Link 19642305 Disease Relevance 1.92 Pain Relevance 0.16
It also interacts with IgA (CD79A; P?
CD79A Binding (interacts) of
16) Confidence 0.30 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2483296 Disease Relevance 0.58 Pain Relevance 0.06
IgM, IgA, C3, and C4 plasma concentrations did not exhibit any consistent association with TCDD levels.
IgA Binding (association) of in plasma
17) Confidence 0.25 Published 2002 Journal Environ Health Perspect Section Abstract Doc Link PMC1241102 Disease Relevance 0.45 Pain Relevance 0.15
Rapidly progressive tabes dorsalis associated with selective IgA deficiency.
IgA Binding (associated) of associated with tabes dorsalis
18) Confidence 0.24 Published 2001 Journal Intern. Med. Section Title Doc Link 11579969 Disease Relevance 0.73 Pain Relevance 0.13
[Pure red cell aplasia developing during the course of primary macroglobulinemia associated with pseudochylothorax and IgA nephropathy].
IgA Binding (associated) of associated with macroglobulinemia, renal disease and aplasia
19) Confidence 0.19 Published 2001 Journal Rinsho Ketsueki Section Title Doc Link 11400302 Disease Relevance 1.64 Pain Relevance 0.09
Most IgM monoclonal gammopathies associated with neuropathy exhibit autoantibody reactivity to neural antigens, but such autoantibody activity has not been associated with IgG or IgA monoclonal gammopathies.
IgA Binding (associated) of in neural associated with paraproteinemias and neuropathic pain
20) Confidence 0.16 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2941760 Disease Relevance 1.78 Pain Relevance 0.05

General Comments

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