INT43909

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Context Info
Confidence 0.48
First Reported 1983
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.45
Pain Relevance 0.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Gcg) extracellular region (Gcg) cytoplasm (Gcg)
Anatomy Link Frequency
plasma 2
Gcg (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Bile 1 92.12 High High
Cholecystokinin 1 91.60 High High
antagonist 1 88.88 High High
isoflurane 2 84.80 Quite High
ketamine 3 82.36 Quite High
anesthesia 3 75.00 Quite High
Disease Link Frequency Relevance Heat
Appetite Loss 13 99.48 Very High Very High Very High
Cancer 77 96.68 Very High Very High Very High
Hyperglycemia 7 92.76 High High
Body Weight 12 85.76 High High
Stress 1 51.56 Quite High
Diabetes Mellitus 1 33.04 Quite Low
Disease 1 32.32 Quite Low
Fetal Weight 3 5.00 Very Low Very Low Very Low
Weight Loss 2 5.00 Very Low Very Low Very Low
Syndrome 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The acute hyperglycemic effect of KX in fed rats was associated with decreased plasma levels of insulin, adrenocorticotropic hormone (ACTH), and corticosterone and increased levels of glucagon and growth hormone (GH).
Positive_regulation (increased) of Gene_expression (levels) of glucagon in plasma
1) Confidence 0.48 Published 2005 Journal Exp. Biol. Med. (Maywood) Section Abstract Doc Link 16246906 Disease Relevance 0.48 Pain Relevance 0.31
Increased glucagon levels can lead to anorexia, as well as increased hepatic gluconeogenesis and utilisation of gluconeogenic amino acids at the expense of protein synthesis, leading to a negative energy balance [25].
Positive_regulation (Increased) of Gene_expression (levels) of glucagon associated with appetite loss
2) Confidence 0.19 Published 2002 Journal BMC Cancer Section Body Doc Link PMC111198 Disease Relevance 0.92 Pain Relevance 0
Hepatic extraction of glucagon did not change in either group of animals.
Positive_regulation (extraction) of Gene_expression (extraction) of glucagon
3) Confidence 0.04 Published 1983 Journal Endocrinology Section Abstract Doc Link 6337043 Disease Relevance 0.05 Pain Relevance 0.14

General Comments

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