INT43947

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Context Info
Confidence 0.68
First Reported 1982
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 11
Total Number 11
Disease Relevance 4.49
Pain Relevance 0.88

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (ASAP1) cytoplasm (ASAP1)
Anatomy Link Frequency
plasma 2
lung 2
glands 1
ASAP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 3 93.32 High High
lidocaine 2 91.68 High High
cva 93 91.60 High High
anesthesia 5 79.48 Quite High
local anesthetic 2 75.00 Quite High
Serotonin 3 72.96 Quite High
Inflammation 2 66.64 Quite High
headache 6 56.48 Quite High
adenocard 2 40.88 Quite Low
aspirin 2 23.60 Low Low
Disease Link Frequency Relevance Heat
Pulmonary Alveolar Proteinosis 35 100.00 Very High Very High Very High
Recurrence 1 100.00 Very High Very High Very High
Fever 1 99.00 Very High Very High Very High
Cancer 2 97.36 Very High Very High Very High
Necrosis 4 96.68 Very High Very High Very High
Hypertension 27 96.16 Very High Very High Very High
Cv General 2 Under Development 92 96.00 Very High Very High Very High
Pressure And Volume Under Development 7 95.32 Very High Very High Very High
Pancreatitis 4 93.32 High High
Pressure Volume 2 Under Development 3 93.28 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The 120 patients were divided in two groups according to the PAPs levels before release of the vascular clamps: group 1 (22 patients) with a mean PAP (PAP) of less than or equal to 20 mm Hg and a diastolic PAP (DPAP) of less than or equal to 15 mm Hg was compared with group 2 (98 patients) with a PAP of greater than 20 mm Hg and a DPAP of greater than 15 mm Hg.
Localization (release) of PAP
1) Confidence 0.68 Published 1982 Journal Transplantation Section Abstract Doc Link 6755828 Disease Relevance 0.44 Pain Relevance 0.15
These five include known inhibitors (quercetin, DBHD, PLP, and PCP), as well as isoprenaline, which binds to SULT1B1 only in the absence of PAP and is a poor substrate for this enzyme (Tables 1 and 2).
Neg (absence) Localization (absence) of PAP
2) Confidence 0.61 Published 2007 Journal PLoS Biology Section Body Doc Link PMC1847840 Disease Relevance 0.13 Pain Relevance 0.03
Thirdly, it is possible that the dose of epoprostenol was not sufficient to decrease PAP.
Localization (decrease) of PAP
3) Confidence 0.58 Published 2010 Journal BMC Pulm Med Section Body Doc Link PMC2859373 Disease Relevance 0.58 Pain Relevance 0.03
The absence of a decrease in systolic PAP in either treatment group may indicate that patients were already past the phase of acute pulmonary vasocontriction.
Localization (decrease) of PAP
4) Confidence 0.51 Published 2010 Journal BMC Pulm Med Section Body Doc Link PMC2859373 Disease Relevance 0.38 Pain Relevance 0.23
Phospholipase A2 was localized with peroxidase anti-peroxidase (PAP)-technique in pancreatic tissue resected from normal portions of tumor-bearing glands of 4 patients and from pancreases of 16 patients suffering from either acute or chronic pancreatitis.
Localization (localized) of PAP in glands associated with cancer and chronic pancreatitis
5) Confidence 0.51 Published 1983 Journal Acta Pathol Microbiol Immunol Scand A Section Abstract Doc Link 6342333 Disease Relevance 0.35 Pain Relevance 0.17
Measurements of systolic PAP, TAPSE, RVFAC, end-diastolic right atrial diameter, end-diastolic right/left ventricular ratio and biochemical parameters of right ventricular overload are presented in Table 2.
Localization (presented) of PAP
6) Confidence 0.48 Published 2010 Journal BMC Pulm Med Section Body Doc Link PMC2859373 Disease Relevance 0.17 Pain Relevance 0.06
Correlation between Plasma ANP concentrations with PAP
Localization (Correlation) of PAP in Plasma
7) Confidence 0.38 Published 2008 Journal Cardiovasc Ultrasound Section Body Doc Link PMC2467405 Disease Relevance 0.65 Pain Relevance 0
There were significant positive correlation between plasma ANP concentrations and PAP (r = 0.74; p < 0.05) (Fig 4).


Localization (correlation) of PAP in plasma
8) Confidence 0.38 Published 2008 Journal Cardiovasc Ultrasound Section Body Doc Link PMC2467405 Disease Relevance 0.77 Pain Relevance 0
After 4 years, the patient was newly admitted for fever and hypoxemia, and the lung CT scan revealed the relapse of PAP (Figure 2A).
Localization (relapse) of PAP in lung associated with pulmonary alveolar proteinosis, fever and recurrence
9) Confidence 0.28 Published 2010 Journal Orphanet J Rare Dis Section Body Doc Link PMC2999609 Disease Relevance 0.67 Pain Relevance 0.04
We examined the effects of procaine, bupivacaine, and ropivacaine on experimentally evoked PAP increase and ET-1 release.
Localization (release) of PAP
10) Confidence 0.23 Published 2009 Journal Anesth. Analg. Section Abstract Doc Link 19690261 Disease Relevance 0.35 Pain Relevance 0.17
CONCLUSION: Bupivacaine and ropivacaine attenuated N-formyl-L-leucine-methionyl-L-phenylalanine-induced PAP, reduced lung edema, and diminished ET-1 release.
Localization (release) of PAP in lung
11) Confidence 0.21 Published 2009 Journal Anesth. Analg. Section Body Doc Link 19690261 Disease Relevance 0 Pain Relevance 0

General Comments

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