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Context Info
Confidence 0.34
First Reported 1975
Last Reported 1975
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.19
Pain Relevance 0.39

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oxidoreductase activity (Scd1) endoplasmic reticulum (Scd1)
Scd1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Delta-9-tetrahydrocannabinol 2 95.74 Very High Very High Very High
Morphine 3 94.08 High High
narcan 2 86.12 High High
Disease Link Frequency Relevance Heat
Diarrhoea 1 99.88 Very High Very High Very High
Body Weight 1 88.36 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Treatment with delta-9-tetrahydrocannabinol (2, 5, or 10 milligrams per kilogram) 1 hour before maloxone administration significantly reduced the intensity of abstinence; the two higher doses blocked the appearance of wet shakes and escapes, diarrhea, and increased defecation. delta-9-Tetrahydrocannabinol did not induce abstinence itself, and prior treatment with cannabidiol was ineffective in reducing naloxoneprecipitated abstinence in animals with morphine pellets.
Positive_regulation (increased) of delta-9-Tetrahydrocannabinol associated with diarrhoea, delta-9-tetrahydrocannabinol and morphine
1) Confidence 0.34 Published 1975 Journal Science Section Abstract Doc Link 1167428 Disease Relevance 0.19 Pain Relevance 0.39

General Comments

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