INT44409

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Context Info
Confidence 0.59
First Reported 1982
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Fen1) mitochondrion (Fen1) nucleolus (Fen1)
nucleus (Fen1) DNA binding (Fen1)
Anatomy Link Frequency
plasma 1
Fen1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
fluoxetine 8 98.20 Very High Very High Very High
Serotonin 1 96.84 Very High Very High Very High
antagonist 1 86.96 High High
Disease Link Frequency Relevance Heat
Appetite Loss 1 36.08 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To assess the involvement of the serotonin (5-HT) system in elicitation of the FEN cue, 5-HT compounds were tested for their ability to substitute for or to antagonize the the discriminative stimulus produced by FEN.
Gene_expression (produced) of FEN associated with serotonin
1) Confidence 0.59 Published 1984 Journal Psychopharmacology (Berl.) Section Abstract Doc Link 6431469 Disease Relevance 0 Pain Relevance 0.22
The limits of detection for Fen, Phen, E, NE and 2-PEA in plasma ranged from 0.32 to 22.9 pmol on column at a signal-to-noise ratio of 3.
Gene_expression (detection) of Fen in plasma
2) Confidence 0.55 Published 2001 Journal Biomed. Chromatogr. Section Abstract Doc Link 11559922 Disease Relevance 0 Pain Relevance 0.06
When testing occurred 8 h after drug treatment, a time when 5-HT level are unaltered by FXT and are maximally reduced by FEN, these drugs had no effect on avoidance acquisition, but FEN produced an increase in intertrial responses whereas FXT did not.
Gene_expression (produced) of FEN associated with fluoxetine
3) Confidence 0.53 Published 1982 Journal Psychopharmacology (Berl.) Section Abstract Doc Link 6813897 Disease Relevance 0 Pain Relevance 0.44

General Comments

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