INT44411

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Context Info
Confidence 0.49
First Reported 1984
Last Reported 2002
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.76
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Fen1) mitochondrion (Fen1) nucleolus (Fen1)
nucleus (Fen1) DNA binding (Fen1)
Fen1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Serotonin 2 99.04 Very High Very High Very High
fluoxetine 3 98.82 Very High Very High Very High
antagonist 1 72.32 Quite High
Disease Link Frequency Relevance Heat
Appetite Loss 1 97.68 Very High Very High Very High
Obesity 9 88.16 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, NE depletion by FEN could be blocked with fluoxetine (10 mg/kg ip) pretreatment, indicating that the action of FEN is mediated through the release of serotonin.
Positive_regulation (mediated) of FEN associated with serotonin and fluoxetine
1) Confidence 0.49 Published 2002 Journal Pharmacol. Biochem. Behav. Section Abstract Doc Link 12151039 Disease Relevance 0.66 Pain Relevance 0.15
These results suggest that the cue properties of FEN might be partially mediated through an interaction with the 5-HT system.
Spec (partially) Positive_regulation (mediated) of FEN
2) Confidence 0.44 Published 1984 Journal Psychopharmacology (Berl.) Section Abstract Doc Link 6431469 Disease Relevance 0.10 Pain Relevance 0.24

General Comments

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