INT44426

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Context Info
Confidence 0.78
First Reported 1981
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 4.02
Pain Relevance 2.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (BRD2)
BRD2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 2 99.62 Very High Very High Very High
narcan 6 99.42 Very High Very High Very High
Enkephalin 4 99.42 Very High Very High Very High
Analgesic 2 98.42 Very High Very High Very High
opiate 3 98.22 Very High Very High Very High
butorphanol 3 97.68 Very High Very High Very High
agonist 1 94.72 High High
antagonist 1 92.32 High High
Spinal cord 4 91.88 High High
cva 1 87.36 High High
Disease Link Frequency Relevance Heat
Cancer 45 100.00 Very High Very High Very High
Hypopituitarism 8 100.00 Very High Very High Very High
Thrombosis 1 96.84 Very High Very High Very High
Reprotox - General 1 8 96.48 Very High Very High Very High
Adenoma 28 96.24 Very High Very High Very High
Recurrence 6 93.76 High High
Endometriosis (extended) 2 92.52 High High
Pituitary Cancer 21 91.96 High High
Cv General 3 Under Development 1 87.36 High High
Headache 9 84.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Patients with deficient FSH, LH, ACTH, or TSH secretion were considered hypopituitary.
Localization (secretion) of FSH
1) Confidence 0.78 Published 2000 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 10843153 Disease Relevance 1.58 Pain Relevance 0.40
The LH and FSH basal secretions were decreased and there were low delayed secretions of LH and FSH after intravenous injection of 100 micrograms LHRH.
Localization (secretions) of FSH
2) Confidence 0.78 Published 2000 Journal Rinsho Shinkeigaku Section Abstract Doc Link 10885339 Disease Relevance 0.56 Pain Relevance 0.29
The LH and FSH basal secretions were decreased and there were low delayed secretions of LH and FSH after intravenous injection of 100 micrograms LHRH.
Localization (secretions) of FSH
3) Confidence 0.78 Published 2000 Journal Rinsho Shinkeigaku Section Abstract Doc Link 10885339 Disease Relevance 0.56 Pain Relevance 0.28
One patient who had an ACTH-secreting tumor exhibited signs of mild hypopituitarism (FSH level, 0.3 ┬ÁL/L).
Localization (secreting) of FSH associated with cancer and hypopituitarism
4) Confidence 0.73 Published 2010 Journal Surgical Neurology International Section Body Doc Link PMC2940085 Disease Relevance 1.17 Pain Relevance 0
The i.m. administration to 6 healthy adult male volunteers of 2 mg butorphanol, a potent synthetic opiate analgesic, resulted in a significant rise in serum PRL level, without affecting GH, LH, FSH, TSH or cortisol secretion.
Localization (secretion) of FSH associated with analgesic, butorphanol and opiate
5) Confidence 0.65 Published 1984 Journal Eur. J. Clin. Pharmacol. Section Abstract Doc Link 6432552 Disease Relevance 0 Pain Relevance 0.82
The opioid control of LH and FSH release: effects of a met-enkephalin analogue and naloxone.
Localization (release) of FSH associated with narcan, enkephalin and opioid
6) Confidence 0.63 Published 1981 Journal Clin. Endocrinol. (Oxf) Section Title Doc Link 6784982 Disease Relevance 0.16 Pain Relevance 0.80

General Comments

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