INT44441

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Context Info
Confidence 0.15
First Reported 1984
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.86
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (FSHR) signal transduction (GNRH1) extracellular space (GNRH1)
extracellular region (GNRH1) plasma membrane (FSHR) signal transducer activity (FSHR)
Anatomy Link Frequency
follicle 2
GNRH1 (Homo sapiens)
FSHR (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 1 98.36 Very High Very High Very High
Calcium channel 1 95.44 Very High Very High Very High
antagonist 3 82.84 Quite High
depression 15 5.00 Very Low Very Low Very Low
rheumatoid arthritis 7 5.00 Very Low Very Low Very Low
opiate 4 5.00 Very Low Very Low Very Low
Opioid 4 5.00 Very Low Very Low Very Low
fluoxetine 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv General 3 Under Development 1 98.36 Very High Very High Very High
Androgen Insensitivity 1 91.12 High High
Coronary Artery Disease 8 86.76 High High
Reprotox - General 1 9 84.40 Quite High
Turner's Syndrome 1 81.56 Quite High
Acne 1 80.64 Quite High
Virilism 1 75.96 Quite High
Gynecomastia 1 73.36 Quite High
Hypogonadotropic Hypogonadism 17 69.76 Quite High
Testosterone Deficiency 2 36.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The hypothalamus increases its secretion of gonadotropin releasing hormone (GnRH) which in turn stimulates the release of luteinizing hormone (LH) and follicle stimulating hormone (FSH).
GnRH Positive_regulation (stimulates) of Localization (release) of follicle stimulating hormone in follicle
1) Confidence 0.15 Published 2007 Journal Clinical Interventions in Aging Section Body Doc Link PMC2686330 Disease Relevance 0.68 Pain Relevance 0
To see if a similar effect could be detected after their chronic administration, we studied the basal, TRH- and LHRH-stimulated TSH, PRL, LH and FSH release in 18 male subjects with chronic stable angina before and on the 30th day of oral treatment with verapamil (n = 8;80 mg three times a day) or with nifedipine (n = 10; 10 mg three times a day).
LHRH-stimulated Positive_regulation (stimulated) of Localization (release) of FSH associated with angina
2) Confidence 0.05 Published 1984 Journal Clin. Endocrinol. (Oxf) Section Abstract Doc Link 6434209 Disease Relevance 0.19 Pain Relevance 0.26

General Comments

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