INT44550

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.70
First Reported 1982
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 38
Total Number 39
Disease Relevance 22.27
Pain Relevance 8.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transport (AVP) cell-cell signaling (AVP) response to stress (AVP)
signal transducer activity (AVP) cytosol (AVP) extracellular space (AVP)
Anatomy Link Frequency
plasma 26
skin 4
nucleus 4
corticotroph 4
neurons 2
AVP (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 23 100.00 Very High Very High Very High
Serotonin 46 99.92 Very High Very High Very High
narcan 32 99.80 Very High Very High Very High
alcohol 32 99.68 Very High Very High Very High
Neuropeptide 167 99.52 Very High Very High Very High
withdrawal 13 99.02 Very High Very High Very High
epidural 6 98.96 Very High Very High Very High
analgesia 9 98.24 Very High Very High Very High
rapifen 7 96.72 Very High Very High Very High
Inflammation 28 96.28 Very High Very High Very High
Disease Link Frequency Relevance Heat
Anxiety Disorder 64 99.88 Very High Very High Very High
Cv General 2 Under Development 225 99.84 Very High Very High Very High
Hyponatremia 425 99.70 Very High Very High Very High
Lung Cancer 77 99.70 Very High Very High Very High
Syndrome 33 99.68 Very High Very High Very High
Carcinoma 2 99.56 Very High Very High Very High
Bacterial Infection 4 99.48 Very High Very High Very High
Sepsis 88 99.08 Very High Very High Very High
Pressure Volume 2 Under Development 98 98.68 Very High Very High Very High
Hepatotoxicity 4 98.36 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
With respect to the effect of estrogen on central neuropeptide transmission, estrogen stimulates the expression of the arginine vasopressin (AVP) gene in the bed nucleus of the stria terminalis (BNST) in rodents.
Positive_regulation (stimulates) of Gene_expression (expression) of AVP in nucleus associated with neuropeptide
1) Confidence 0.70 Published 1996 Journal Cell. Mol. Neurobiol. Section Abstract Doc Link 8818400 Disease Relevance 0.67 Pain Relevance 0.50
The basic mechanism is straightforward: MDMA causes excess antidiuretic hormone (ADH) production and thus a reduced renal response to water loading, so that excess fluid ingestion following MDMA leads to dilutional hyponatraemia and cerebral oedema [18].
Positive_regulation (causes) of Gene_expression (production) of ADH associated with hyponatremia and pressure and volume under development
2) Confidence 0.67 Published 2008 Journal Crit Care Section Body Doc Link PMC2374627 Disease Relevance 2.02 Pain Relevance 0.63
The synthesis and release of AVP may also be induced by nonosmotic stimuli including hypovolemia, a fall in arterial blood pressure, neural regulation by various hypothalamic neurotransmitters and neuropeptides, and many pharmacological agents.
Positive_regulation (induced) of Gene_expression (synthesis) of AVP in neural associated with neurotransmitter, pressure volume 2 under development and neuropeptide
3) Confidence 0.64 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2504060 Disease Relevance 0.31 Pain Relevance 0.39
The resultant cell-volume shrinkage or increased intracellular osmolality, or both, in turn initiate a cascade of events that lead to the augmentation of both AVP synthesis and release (Robinson et al 1990).
Positive_regulation (augmentation) of Gene_expression (synthesis) of AVP
4) Confidence 0.64 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2504060 Disease Relevance 0.13 Pain Relevance 0.14
During the control test, exercise significantly increased plasma AVP levels, with a peak value five times higher than baseline.
Positive_regulation (increased) of Gene_expression (levels) of AVP in plasma
5) Confidence 0.50 Published 2009 Journal J Neural Transm Section Abstract Doc Link 19649691 Disease Relevance 0 Pain Relevance 0.38
With respect to the effect of estrogen on central neuropeptide transmission, estrogen stimulates the expression of the arginine vasopressin (AVP) gene in the bed nucleus of the stria terminalis (BNST) in rodents.
Positive_regulation (stimulates) of Gene_expression (expression) of arginine vasopressin in nucleus associated with neuropeptide
6) Confidence 0.50 Published 1996 Journal Cell. Mol. Neurobiol. Section Abstract Doc Link 8818400 Disease Relevance 0.67 Pain Relevance 0.50
Should only patients with documented inappropriate vasopressin levels be included?
Positive_regulation (documented) of Gene_expression (levels) of vasopressin
7) Confidence 0.50 Published 2005 Journal Crit Care Section Body Doc Link PMC1175907 Disease Relevance 0.32 Pain Relevance 0.17
Plasma concentrations of vasopressin in shock
Positive_regulation (concentrations) of Gene_expression (concentrations) of vasopressin in Plasma associated with cv general 2 under development
8) Confidence 0.50 Published 2005 Journal Crit Care Section Body Doc Link PMC1175907 Disease Relevance 0.65 Pain Relevance 0.34
Should only patients with documented inappropriate vasopressin levels be included?
Positive_regulation (inappropriate) of Gene_expression (levels) of vasopressin
9) Confidence 0.50 Published 2005 Journal Crit Care Section Body Doc Link PMC1175907 Disease Relevance 0.32 Pain Relevance 0.17
Sustained elevation of vasopressin plasma levels in healthy young men, but not in abstinent alcoholics, upon expectation of novelty.
Positive_regulation (elevation) of Neg (not) Gene_expression (levels) of vasopressin in plasma associated with narcan
10) Confidence 0.50 Published 1997 Journal Psychoneuroendocrinology Section Title Doc Link 9141148 Disease Relevance 0.34 Pain Relevance 0.22
[Variations in vasopressin (ADH)-levels during NLA combined with epidural fentanyl-analgesia (author's transl)].
Positive_regulation ([Variations) of Gene_expression (-levels) of ADH associated with epidural and analgesia
11) Confidence 0.49 Published 1982 Journal Reg Anaesth Section Title Doc Link 7071395 Disease Relevance 0 Pain Relevance 0.58
[Variations in vasopressin (ADH)-levels during NLA combined with epidural fentanyl-analgesia (author's transl)].
Positive_regulation ([Variations) of Gene_expression (-levels) of vasopressin associated with epidural and analgesia
12) Confidence 0.49 Published 1982 Journal Reg Anaesth Section Title Doc Link 7071395 Disease Relevance 0 Pain Relevance 0.58
Interestingly, patients with OCD show elevated basal levels of AVP in the cerebrospinal fluid and exaggerated plasma levels of AVP in response to hypertonic challenge [16].
Positive_regulation (elevated) of Gene_expression (levels) of AVP in plasma associated with anxiety disorder
13) Confidence 0.49 Published 2001 Journal BMC Neurosci Section Body Doc Link PMC55332 Disease Relevance 0.94 Pain Relevance 0.22
Blood samples were obtained by peripheral vein puncture before the induction of anesthesia, then 2, 4, 6, 8, 24, 48, and 72 h after skin incision to measure the levels of serum IL-6, adrenocorticotropic hormone (ACTH), cortisol, and antidiuretic hormone (ADH).
Positive_regulation (induction) of Gene_expression (levels) of ADH in skin associated with anesthesia
14) Confidence 0.49 Published 2000 Journal Surg. Today Section Abstract Doc Link 10664330 Disease Relevance 0.15 Pain Relevance 0.18
The basic mechanism is straightforward: MDMA causes excess antidiuretic hormone (ADH) production and thus a reduced renal response to water loading, so that excess fluid ingestion following MDMA leads to dilutional hyponatraemia and cerebral oedema [18].
Positive_regulation (causes) of Gene_expression (production) of ADH associated with hyponatremia and pressure and volume under development
15) Confidence 0.49 Published 2008 Journal Crit Care Section Body Doc Link PMC2374627 Disease Relevance 2.02 Pain Relevance 0.63
In addition, he developed SIADH-like symptoms, and we strongly suspected that it was due to ectopic production of ADH from this carcinoma.
Positive_regulation (due) of Gene_expression (production) of ADH associated with hyponatremia and carcinoma
16) Confidence 0.47 Published 2004 Journal Nippon Hinyokika Gakkai Zasshi Section Abstract Doc Link 15354720 Disease Relevance 1.08 Pain Relevance 0.12
Overview of AVP synthesis and release
Positive_regulation (Overview) of Gene_expression (synthesis) of AVP
17) Confidence 0.46 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2504060 Disease Relevance 0.53 Pain Relevance 0.12
Rebound hyponatremia may occur following withdrawal of conivaptan therapy because of a compensatory rise in plasma AVP levels during the treatment period.
Positive_regulation (rise) of Gene_expression (levels) of AVP in plasma associated with hyponatremia and withdrawal
18) Confidence 0.46 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2504060 Disease Relevance 0.95 Pain Relevance 0.11
Our findings contrast with previous studies with other anesthetics, including fentanyl, in which plasma levels of ADH and GH become markedly elevated during bypass.
Positive_regulation (elevated) of Gene_expression (levels) of ADH in plasma
19) Confidence 0.46 Published 1982 Journal Anesth. Analg. Section Abstract Doc Link 6461279 Disease Relevance 0.09 Pain Relevance 0.56
Mechanisms of the hepatotoxicity of ethanol are reviewed, including effects resulting from alcohol dehydrogenase (ADH) mediated excessive hepatic generation of NADH and acetaldehyde.
Positive_regulation (mediated) of Gene_expression (generation) of ADH associated with hepatotoxicity and alcohol
20) Confidence 0.36 Published 1994 Journal Ann. Med. Section Abstract Doc Link 7826592 Disease Relevance 0.15 Pain Relevance 0.08

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox