INT44614

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Context Info
Confidence 0.29
First Reported 1984
Last Reported 2010
Negated 1
Speculated 0
Reported most in Abstract
Documents 7
Total Number 8
Disease Relevance 5.60
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (FCGR2C) cytoplasm (FCGR2C)
Anatomy Link Frequency
TFK-1 1
EGI-1 1
eosinophil 1
mast cell 1
FCGR2C (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 2 100.00 Very High Very High Very High
abdominal pain 2 99.16 Very High Very High Very High
tolerance 2 89.20 High High
palliative 8 70.12 Quite High
midbrain 20 68.72 Quite High
Dopamine 83 68.00 Quite High
Bile 13 65.88 Quite High
antagonist 17 27.52 Quite Low
Inflammation 5 25.00 Low Low
Pain 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 6 100.00 Very High Very High Very High
Abdominal Pain 2 99.16 Very High Very High Very High
Eosinophilia 1 98.72 Very High Very High Very High
Splenomegaly 1 98.16 Very High Very High Very High
Enteritis 1 97.54 Very High Very High Very High
Rhinitis 1 97.34 Very High Very High Very High
Infection 6 96.46 Very High Very High Very High
Hepatitis C Virus Infection 2 95.84 Very High Very High Very High
Hepatitis 3 94.92 High High
Apoptosis 28 94.56 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Absence of apolipoprotein C-II (and its isoforms C-II1 and C-II2) was documented by a sensitive and specific radioimmunoassay, analytical isoelectric focusing, and in vitro lipolytic assay.
Neg (Absence) Gene_expression (Absence) of C-II associated with disorder of lipid metabolism
1) Confidence 0.29 Published 1984 Journal Am. J. Med. Section Abstract Doc Link 6475985 Disease Relevance 0.77 Pain Relevance 0.10
In addition, previous focused gene expression array revealed that IGFR1, IGFR2 and CXCR4 were expressed in undifferentiated BG03 hESC [32].
Gene_expression (expressed) of IGFR2
2) Confidence 0.24 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2719871 Disease Relevance 0 Pain Relevance 0.13
IGFR2 expression was confirmed in EGI-1 and TFK-1.
Gene_expression (expression) of IGFR2 in TFK-1
3) Confidence 0.19 Published 2010 Journal BMC Cancer Section Abstract Doc Link PMC2896958 Disease Relevance 0.86 Pain Relevance 0.10
The EARLY trial provides clear evidence for treating the FC II patient; this is supported by sub-group data from other trials, eg, ARIES.36,44
Gene_expression (patient) of FC II
4) Confidence 0.17 Published 2009 Journal Vascular Health and Risk Management Section Body Doc Link PMC2725793 Disease Relevance 0.75 Pain Relevance 0.04
IGFR2 expression was confirmed in EGI-1 and TFK-1.
Gene_expression (expression) of IGFR2 in EGI-1
5) Confidence 0.06 Published 2010 Journal BMC Cancer Section Abstract Doc Link PMC2896958 Disease Relevance 0.86 Pain Relevance 0.10
Most zoonotic helminthes induced immune response (Nutman, 2001) characterized by producing of type 2 cytokines, Ig G1, IgG2, IgE antibodies and eosinophil and mast cell activation (Hoffman et al., 2002).
Gene_expression (producing) of IgG2 in mast cell associated with cytokine
6) Confidence 0.02 Published 2008 Journal J Egypt Soc Parasitol Section Abstract Doc Link 19209761 Disease Relevance 0.68 Pain Relevance 0.05
Most zoonotic helminthes induced immune response (Nutman, 2001) characterized by producing of type 2 cytokines, Ig G1, IgG2, IgE antibodies and eosinophil and mast cell activation (Hoffman et al., 2002).
Gene_expression (producing) of IgG2 in eosinophil associated with cytokine
7) Confidence 0.01 Published 2008 Journal J Egypt Soc Parasitol Section Abstract Doc Link 19209761 Disease Relevance 0.68 Pain Relevance 0.05
Twenty sera from patients with suspected enteric infection with A. caninum (manifested as eosinophilic enteritis or unexplained abdominal pain with peripheral eosinophilia) were tested; 16 had total IgG antibodies to Ac68, while IgG1, IgG2, IgG3, and IgG4 responses were found in 11, 10, 9, and 12 of these sera, respectively.
Gene_expression (found) of IgG2 associated with rhinitis, abdominal pain, enteritis, eosinophilia and infection
8) Confidence 0.01 Published 1996 Journal Am. J. Trop. Med. Hyg. Section Abstract Doc Link 8686791 Disease Relevance 0.98 Pain Relevance 0.10

General Comments

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