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Context Info
Confidence 0.45
First Reported 1984
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 0.87
Pain Relevance 1.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Chat) transferase activity, transferring acyl groups (Chat)
Anatomy Link Frequency
neuronal 1
nerves 1
brain 1
striatum 1
Chat (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dopamine receptor 1 100.00 Very High Very High Very High
Substantia nigra 2 99.32 Very High Very High Very High
qutenza 8 97.92 Very High Very High Very High
gABA 2 97.76 Very High Very High Very High
Neurotransmitter 2 90.80 High High
Eae 8 79.52 Quite High
substance P 3 78.40 Quite High
Intracerebroventricular 1 75.72 Quite High
Dynorphin 1 65.36 Quite High
Enkephalin 1 63.68 Quite High
Disease Link Frequency Relevance Heat
Alzheimer's Dementia 22 98.72 Very High Very High Very High
Amnesia 8 96.16 Very High Very High Very High
Cognitive Disorder 38 93.20 High High
Congenital Anomalies 1 87.36 High High
Gliosis 2 82.08 Quite High
Cv General 3 Under Development 2 73.68 Quite High
Aging 7 50.00 Quite Low
Death 1 46.72 Quite Low
Parkinson's Disease 1 42.40 Quite Low
Disease 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The activities of choline acetyltransferase and cholinesterase and the binding activity of muscarinic receptor were determined.
choline acetyltransferase Binding (binding) of
1) Confidence 0.45 Published 2005 Journal Beijing Da Xue Xue Bao Section Body Doc Link 16378114 Disease Relevance 0.07 Pain Relevance 0
NADPH diaphorase was selected for staining rather than choline acetyl transforase (ChAT) since it provides better resolution of neuronal processes in the region of the pedunculopontine tegmental nucleus.
ChAT Binding (staining) of in neuronal
2) Confidence 0.29 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2257968 Disease Relevance 0.16 Pain Relevance 0
Dicholine salt of succinic acid improves learning and increases activity of brain choline acetyltransferase in rats with ?
choline acetyltransferase Binding (activity) of in brain
3) Confidence 0.16 Published 2008 Journal BMC Pharmacol Section Body Doc Link PMC2262060 Disease Relevance 0.55 Pain Relevance 0
Thus, [3H]GABA uptake and [3H]tiagabine/GABA uptake sites in striatal target tissues (globus pallidus and substantia nigra), as well as [3H]choline uptake, choline acetyltransferase activity and dopamine receptor binding in the striatum were decreased by the toxin and restored to varying degrees by glial cell line-derived neurotrophic factor administration.
choline acetyltransferase Binding (binding) of in striatum associated with gaba, dopamine receptor and substantia nigra
4) Confidence 0.13 Published 1998 Journal Neuroscience Section Abstract Doc Link 9483508 Disease Relevance 0.09 Pain Relevance 0.48
As indices of cholinergic nerves, activities of choline acetyltransferase and acetylcholinesterase were also unchanged after capsaicin treatment.
choline acetyltransferase Binding (activities) of in nerves associated with qutenza
5) Confidence 0.12 Published 1984 Journal Brain Res. Section Abstract Doc Link 6478198 Disease Relevance 0 Pain Relevance 0.67

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