INT44696

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Context Info
Confidence 0.64
First Reported 1984
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 3.10
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Baat) peroxisome (Baat) transferase activity, transferring acyl groups (Baat)
molecular_function (Baat) lipid metabolic process (Baat)
Anatomy Link Frequency
poly 1
BAT 1
heart 1
Baat (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Intracerebroventricular 6 95.80 Very High Very High Very High
opioid receptor 1 83.96 Quite High
Opioid 1 80.80 Quite High
antagonist 2 80.24 Quite High
narcan 1 79.36 Quite High
Morphine 3 75.00 Quite High
Raphe 1 64.64 Quite High
Rostral ventrolateral medulla 3 43.84 Quite Low
opiate 2 32.24 Quite Low
addiction 1 25.60 Quite Low
Disease Link Frequency Relevance Heat
Obesity 115 100.00 Very High Very High Very High
Hypoxia 136 94.40 High High
Stress 4 88.12 High High
Breast Cancer 2 78.32 Quite High
Cancer 10 76.96 Quite High
Disease 3 76.12 Quite High
Fever 8 75.00 Quite High
Apnoea 28 60.92 Quite High
Weight Loss 12 50.00 Quite Low
Body Weight 14 40.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
By contrast, isoproterenol HCl (0.5 mg/kg i.p.), known to activate BAT heat production, given to rats kept at 4 or 21 degrees C raised the TIBATS significantly above changes seen in TRS.
Gene_expression (production) of BAT in BAT associated with obesity
1) Confidence 0.64 Published 1984 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 6491989 Disease Relevance 0.60 Pain Relevance 0.23
Increases in brown adipose tissue (BAT) sympathetic nerve activity (SNA) (peak, +326% of control), BAT temperature (peak, +0.8 degrees C), renal SNA (peak, +146% of control), and heart rate (HR; peak, +32 beats/min) produced by intravenous fentanyl were abolished by premamillary transection of the neuraxis but were mimicked by intracerebroventricular administration of fentanyl, which also increased arterial pressure (AP; peak, +12 mmHg).
Gene_expression (produced) of BAT in heart associated with obesity and intracerebroventricular
2) Confidence 0.46 Published 2005 Journal Am. J. Physiol. Regul. Integr. Comp. Physiol. Section Abstract Doc Link 15576661 Disease Relevance 0.50 Pain Relevance 0.35
The BAT was removed and weighed immediately after that in the two groups.
Gene_expression (removed) of BAT associated with obesity
3) Confidence 0.27 Published 2008 Journal Lipids Health Dis Section Body Doc Link PMC2515839 Disease Relevance 0.80 Pain Relevance 0
The BAT was removed and weighed immediately after that in the two groups.
Gene_expression (weighed) of BAT associated with obesity
4) Confidence 0.27 Published 2008 Journal Lipids Health Dis Section Body Doc Link PMC2515839 Disease Relevance 0.85 Pain Relevance 0
In 2005, Liu et al. synthesized poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide)-b-poly(D,L-lactide-co-glycolide) micelles for controlled paclitaxel delivery [36].
Gene_expression (synthesized) of N-isopropylacrylamide-co-N in poly
5) Confidence 0.02 Published 2010 Journal J Biol Eng Section Body Doc Link PMC3002303 Disease Relevance 0.35 Pain Relevance 0

General Comments

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