INT4471

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Context Info
Confidence 0.36
First Reported 1975
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 1.92
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Gprasp1) cytoplasm (Gprasp1)
Gprasp1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
lidocaine 6 97.72 Very High Very High Very High
antidepressant 3 93.16 High High
anticonvulsant 3 92.48 High High
Physical dependence 3 85.68 High High
Central nervous system 23 61.72 Quite High
Analgesic 3 5.00 Very Low Very Low Very Low
Paracetamol 3 5.00 Very Low Very Low Very Low
Calcium channel 3 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 129 98.88 Very High Very High Very High
Hip Fractures 3 88.36 High High
Drug Dependence 3 85.68 High High
Aging 6 80.72 Quite High
Parasitic Infection 6 79.20 Quite High
Congenital Anomalies 2 79.12 Quite High
Respiratory Disease 8 54.64 Quite High
Lower Respiratory Tract Infection 4 52.56 Quite High
Cardiovascular Disease 8 43.44 Quite Low
Diabetes Mellitus 10 37.08 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The number of PIPs increased as variability in firing rate decreased after lidocaine.
Negative_regulation (number) of PIPs associated with lidocaine
1) Confidence 0.36 Published 1975 Journal Brain Res. Section Abstract Doc Link 1174979 Disease Relevance 0 Pain Relevance 0.41
Recent studies in long-term care settings showed that physician or pharmacist interventions reduce PIPs [1,12,16,43], while a clinical review program of prescriptions for community-dwelling patients conducted by a team of physicians, pharmacists and nurses did not seem to improve prescribing practices [44].


Negative_regulation (reduce) of PIPs
2) Confidence 0.29 Published 2004 Journal BMC Geriatr Section Body Doc Link PMC529256 Disease Relevance 0.07 Pain Relevance 0
Although the association between length of stay and the likelihood of receiving a PIP in nursing homes was studied in the past [6], to our knowledge, this is the first time it is being shown to be a predictor of PIPs.
Negative_regulation (predictor) of PIPs
3) Confidence 0.29 Published 2004 Journal BMC Geriatr Section Body Doc Link PMC529256 Disease Relevance 0.34 Pain Relevance 0.15
The length of stay was positively associated with PIPs, while the prevalence of PIPs decreased with age.
Negative_regulation (prevalence) of PIPs
4) Confidence 0.29 Published 2004 Journal BMC Geriatr Section Body Doc Link PMC529256 Disease Relevance 0.32 Pain Relevance 0.19
On the contrary, the number of agreed PIPs was not associated with the number of DALYs and deaths among children under 15 years.
Negative_regulation (number) of PIPs
5) Confidence 0.14 Published 2010 Journal Popul Health Metr Section Body Doc Link PMC3017015 Disease Relevance 0.73 Pain Relevance 0
No evidence of association was found between the number of PIPs and the regional burden of disease in children under 15 years (DALYs: ?
Negative_regulation (number) of PIPs associated with disease
6) Confidence 0.14 Published 2010 Journal Popul Health Metr Section Body Doc Link PMC3017015 Disease Relevance 0.45 Pain Relevance 0

General Comments

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