INT44717
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
Flow cytometry analysis demonstrates a monoclonal pattern of immunoglobulin light chain expression. | |||||||||||||||
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Multiple myeloma is characterized by the production of a monoclonal immunoglobulin, free monoclonal light chains, or both. | |||||||||||||||
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Biopsy of the mass revealed immature plasmacytes with very faint cytoplasmic expression of kappa light chains. | |||||||||||||||
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CXCR3 binding chemokine and TNFSF14 over expression in bladder urothelium of patients with ulcerative interstitial cystitis. | |||||||||||||||
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A kappa-light chain M component and kappa-light chain-restricted bone marrow plasmacytosis were detected. | |||||||||||||||
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Further tests, including immunoglobulin electrophoresis and assay of the serum levels of kappa and lambda light chains, demonstrated that his myeloma was of the IgM, kappa subtype. | |||||||||||||||
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CSF measurements included immunoglobulin G (IgG) synthesis, IgG ratio, myelin basic protein, IgG kappa light chains, and oligoclonal banding. | |||||||||||||||
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Diagnosis of acute myocardial infarction by detection of circulating cardiac myosin light chains. | |||||||||||||||
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CONCLUSIONS: Our study using DNA microarray analysis followed by quantitative real-time polymerase chain reaction reveals over expression of genes related to immune and inflammatory responses, including T-helper type 1 related chemokines, and cytokines such as CXCR3 binding chemokines and TNFSF14. | |||||||||||||||
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The sister still alive showed renal impairment and deep venous thrombosis associated with lupus anticoagulant activity, decrease of circulating autoreactive CD5 (+) B lymphocytes and increased urinary levels of IgG and kappa and lambda light chains, suggesting a possible defect in regulation of B-lymphocyte function. | |||||||||||||||
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Enhanced plasma levels of LIGHT in unstable angina: possible pathogenic role in foam cell formation and thrombosis. | |||||||||||||||
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LTG, with its Na+ channel blocking actions, was initially introduced for add-on therapy of focal seizures in adults, but it was rapidly demonstrated that it was a broad spectrum AED. | |||||||||||||||
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Four AEDs (FBM, LTG, TPM and RUF) have been officially licensed for LGS after demonstrating significant efficacy in randomized, double-blind, placebo controlled studies. | |||||||||||||||
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More recently (Cianchetti et al 2002; Conry 2004), LTG was shown to be effective in West syndrome. | |||||||||||||||
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Titration of LTG thus requires careful attention, especially in children.
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General Comments
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