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Context Info
Confidence 0.27
First Reported 1984
Last Reported 1984
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.27

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small molecule metabolic process (ODC1) lyase activity (ODC1) cytoplasm (PLAT)
cytosol (ODC1) extracellular space (PLAT) protein modification process (PLAT)
Anatomy Link Frequency
skin 2
PLAT (Homo sapiens)
ODC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
lidocaine 1 99.70 Very High Very High Very High
anesthesia 1 91.44 High High
local anesthetic 1 75.00 Quite High


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In preparation for experiments to determine the effects of various orally administered compounds on human skin ornithine decarboxylase (ODC) activity, it was observed that intradermal lidocaine hydrochloride inhibited 12-0-tetradecanoylphorbol-13-acetate (TPA)-induced ODC.
Negative_regulation (inhibited) of TPA Positive_regulation (induced) of ODC in skin associated with lidocaine
1) Confidence 0.27 Published 1984 Journal Anticancer Res. Section Abstract Doc Link 6517531 Disease Relevance 0 Pain Relevance 0.27

General Comments

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