INT44783

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Context Info
Confidence 0.75
First Reported 1984
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.72
Pain Relevance 1.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Chga)
Anatomy Link Frequency
neuron 2
adrenal medulla 1
vesicle 1
Chga (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Enkephalin 5 100.00 Very High Very High Very High
Neuropeptide 3 99.90 Very High Very High Very High
medulla 2 99.36 Very High Very High Very High
Somatostatin 212 96.36 Very High Very High Very High
Catecholamine 3 95.24 Very High Very High Very High
Dopamine 17 91.72 High High
noradrenaline 6 90.80 High High
imagery 12 5.00 Very Low Very Low Very Low
agonist 6 5.00 Very Low Very Low Very Low
Potency 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Exanthema 4 99.96 Very High Very High Very High
Metastasis 28 99.76 Very High Very High Very High
Convulsion 3 99.50 Very High Very High Very High
Glucagonoma 12 92.64 High High
Malignant Neoplastic Disease 10 80.68 Quite High
Hypoglycemia 11 58.32 Quite High
Insulinoma 24 57.28 Quite High
Neuroendocrine Cancer 22 50.00 Quite Low
Carcinoid 44 43.48 Quite Low
Cancer 174 36.24 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The patient had a complete resolution of skin rash, normalisation of plasma glucagon, chromogranin A and neuron specific enolase levels, and metastatic disease stabilisation.
Gene_expression (levels) of chromogranin A in neuron associated with exanthema and metastasis
1) Confidence 0.75 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2845555 Disease Relevance 0.70 Pain Relevance 0.14
On the other hand, chromogranin A, immunologically related proteins and enkephalin-like immunoreactivity were only present in the dense (large dense-core) vesicle population.
Gene_expression (present) of chromogranin A in vesicle associated with enkephalin
2) Confidence 0.65 Published 1984 Journal Neuroscience Section Abstract Doc Link 6527783 Disease Relevance 0 Pain Relevance 0.58
The patient had a complete resolution of skin rash, normalisation of plasma glucagon, chromogranin A and neuron specific enolase levels, and metastatic disease stabilisation.
Gene_expression (normalisation) of chromogranin A in neuron associated with exanthema and metastasis
3) Confidence 0.65 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2845555 Disease Relevance 0.71 Pain Relevance 0.14
Limbic seizures induce neuropeptide and chromogranin mRNA expression in rat adrenal medulla.
Gene_expression (expression) of chromogranin mRNA in adrenal medulla associated with medulla, convulsion, neuropeptide and enkephalin
4) Confidence 0.32 Published 1997 Journal Brain Res. Mol. Brain Res. Section Title Doc Link 9427505 Disease Relevance 0.32 Pain Relevance 0.59

General Comments

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