INT44787

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Context Info
Confidence 0.43
First Reported 1984
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.73
Pain Relevance 1.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Sdcbp) cytoplasm (Sdcbp)
Anatomy Link Frequency
platelets 2
Sdcbp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
aspirin 5 98.76 Very High Very High Very High
qutenza 9 96.96 Very High Very High Very High
ischemia 20 83.60 Quite High
Paracetamol 1 75.00 Quite High
Central nervous system 1 37.92 Quite Low
Inflammation 3 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 1 98.84 Very High Very High Very High
Hemolysis 1 86.72 High High
Cv Unclassified Under Development 13 83.60 Quite High
Acidosis 2 82.96 Quite High
Injury 12 82.56 Quite High
Ocular Hypertension 5 72.88 Quite High
Death 3 52.88 Quite High
Retina Disease 9 51.80 Quite High
Disease 2 50.72 Quite High
Eye Disease 1 48.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PC combination with ASA at therapeutic doses range (50.0 + 50.0 mg/kg) significantly diminished MDA formation, while at subtoxic doses range (250.0 + 250.0 mg/kg) such effect was not detected, although subsequent tendency toward CL intensity reduction was observed.
Negative_regulation (diminished) of MDA Binding (formation) of associated with aspirin
1) Confidence 0.43 Published 1996 Journal Eksp Klin Farmakol Section Abstract Doc Link 8704633 Disease Relevance 0 Pain Relevance 0.25
TMZ has also been reported to reduce the tissue formation of MDA.26 It reduces the oxidative stress which occurs during the reoxygenation phase of the reperfusion, evaluated as a limited reduction in glutathione release.27
Negative_regulation (reduce) of MDA Binding (formation) of associated with stress
2) Confidence 0.12 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2819765 Disease Relevance 0.65 Pain Relevance 0.07
In AA-stimulated platelets, MDA formation was slightly decreased and TXB2 formation was not affected.
Negative_regulation (decreased) of MDA Binding (formation) of in platelets
3) Confidence 0.05 Published 1984 Journal Thromb. Res. Section Abstract Doc Link 6528310 Disease Relevance 0.09 Pain Relevance 0.68

General Comments

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