INT44838

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Context Info
Confidence 0.02
First Reported 1984
Last Reported 1984
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Pitpnm1, Th) mitochondrion (Th) transport (Pitpnm1)
Golgi apparatus (Pitpnm1) endoplasmic reticulum (Pitpnm1) intracellular (Pitpnm1)
Pitpnm1 (Mus musculus)
Th (Mus musculus)
Pain Link Frequency Relevance Heat
withdrawal 3 99.72 Very High Very High Very High
Morphine 5 99.28 Very High Very High Very High
Dopamine 7 99.20 Very High Very High Very High
narcan 1 96.44 Very High Very High Very High
Serotonin 1 88.32 High High
addiction 2 88.20 High High
tolerance 1 87.48 High High
Disease Link Frequency Relevance Heat
Morphine Dependence 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both inhibition of tyrosine hydroxylase by alpha-methyl-p-tyrosine (alpha-MPT) and inhibition of DA receptors by pimozide interfere with the effect of Z-Pro-D-Leu on naloxone-precipitated morphine withdrawal.
alpha-MPT Negative_regulation (inhibition) of tyrosine hydroxylase associated with dopamine, narcan, withdrawal and morphine
1) Confidence 0.02 Published 1984 Journal Pharmacol. Biochem. Behav. Section Abstract Doc Link 6541792 Disease Relevance 0 Pain Relevance 1.09

General Comments

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