INT4488

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Context Info
Confidence 0.41
First Reported 1975
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 10
Total Number 11
Disease Relevance 4.69
Pain Relevance 3.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (TSHB) extracellular region (TSHB) cellular nitrogen compound metabolic process (TSHB)
cell-cell signaling (TSHB)
Anatomy Link Frequency
follicle 3
thyroid 3
pituitary 2
plasma 1
lymphocytes 1
TSHB (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 5 98.36 Very High Very High Very High
opiate 5 98.14 Very High Very High Very High
Morphine 4 98.06 Very High Very High Very High
cINOD 1 97.76 Very High Very High Very High
narcan 4 97.74 Very High Very High Very High
Inflammation 42 95.76 Very High Very High Very High
Migraine 22 95.68 Very High Very High Very High
diclofenac 5 95.56 Very High Very High Very High
Cluster headache 131 91.76 High High
anesthesia 4 91.20 High High
Disease Link Frequency Relevance Heat
Pituitary Cancer 22 99.96 Very High Very High Very High
Adenoma 30 99.88 Very High Very High Very High
Thyroid Disease 19 99.62 Very High Very High Very High
Hypersensitivity 12 98.00 Very High Very High Very High
Disease 64 97.88 Very High Very High Very High
INFLAMMATION 50 97.52 Very High Very High Very High
Headache 64 95.68 Very High Very High Very High
Stress 9 94.80 High High
Cancer 51 94.24 High High
Cluster Headache 133 91.76 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Before and after loading, serum glucose, prolactin (PRL), thyroid stimulating hormone (TSH), luteinizing hormone, follicle stimulating hormone, adrenocorticotropic hormone, cortisol, human growth hormone and beta-endorphin were measured.
Gene_expression (measured) of thyroid stimulating hormone in follicle
1) Confidence 0.41 Published 1989 Journal Cephalalgia Section Abstract Doc Link 2507160 Disease Relevance 0.18 Pain Relevance 0.29
Thyroid stimulating hormone (TSH) and T4 levels were drawn (TSH was 9.02 micro-IU/ml (normal 0.10 to 5.0 micro-IU/ml) and his T4 was 1.6 mcg/dl (normal 4.5 to 13.2 mcg/dl), but the results were not available until after resuscitation).
Gene_expression (drawn) of Thyroid stimulating hormone in Thyroid
2) Confidence 0.34 Published 2008 Journal J Med Case Reports Section Body Doc Link PMC2396176 Disease Relevance 0.31 Pain Relevance 0
Abnormal blood levels of prolactin, testosterone, thyroid stimulating hormone (TSH), and cortisol may be linked to perturbations in the activity of the hypothalamic-pituitary-adrenal axis.
Gene_expression (levels) of thyroid stimulating hormone in pituitary
3) Confidence 0.18 Published 2008 Journal Orphanet J Rare Dis Section Body Doc Link PMC2517059 Disease Relevance 0.99 Pain Relevance 1.26
Thyrotropin alfa is a synthetic recombinant human thyroid stimulating hormone (rhTSH) produced in Chinese hamster ovary cells.
Gene_expression (produced) of thyroid stimulating hormone in ovary
4) Confidence 0.17 Published 2008 Journal OncoTargets and therapy Section Body Doc Link PMC2994210 Disease Relevance 0.30 Pain Relevance 0
Morphine administration in man results in a significant increase in serum prolactin without altering the levels of growth hormone, thyroid stimulating hormone and cortisol.
Gene_expression (levels) of stimulating hormone in thyroid associated with morphine
5) Confidence 0.16 Published 1975 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 1176587 Disease Relevance 0.09 Pain Relevance 0.27
In this study, plasma levels of prolactin, follicle stimulating hormone, luteinizing hormone, thyrotropin and beta-endorphin were determined in 6 healthy men after administration of diclofenac, a prostaglandin synthesis inhibitor.
Spec (determined) Gene_expression (levels) of stimulating hormone in plasma associated with diclofenac
6) Confidence 0.15 Published 1988 Journal Horm. Res. Section Abstract Doc Link 2975630 Disease Relevance 0.10 Pain Relevance 0.24
Some of these pure somatotrope adenomas also express free alpha-subunit, which is common to the glycoprotein hormones follicle-stimulating hormone (FSH), luteinizing hormone (LH), thyroid-stimulating hormone (TSH) and chorionic gonadotropin hormone (CG, co-localized in the same cells or even in the same granules as GH) [36].
Gene_expression (express) of thyroid-stimulating hormone in follicle associated with adenoma
7) Confidence 0.14 Published 2008 Journal Orphanet J Rare Dis Section Body Doc Link PMC2459162 Disease Relevance 2.00 Pain Relevance 0
Serum levels of thyroid stimulating hormone (TSH) and total thyroxine (T4) were only available for 2,299 participants ?
Gene_expression (available) of thyroid stimulating hormone in thyroid
8) Confidence 0.13 Published 2006 Journal Environ Health Perspect Section Body Doc Link PMC1764147 Disease Relevance 0 Pain Relevance 0
For example, during antigen-mediated activation, CD4+ and CD8+ lymphocytes are able to produce hormones like ACTH, growth hormone (GH), thyroid stimulating hormone (TSH) and gonadotropins [28], which may regulate allergy progression.
Gene_expression (produce) of thyroid stimulating hormone in lymphocytes associated with hypersensitivity
9) Confidence 0.02 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2834663 Disease Relevance 0.28 Pain Relevance 0.13
We investigated propofol pharmacokinetics in a patient with secondary hyperthyroidism caused by thyroid stimulating hormone (TSH) producing pituitary adenoma.
Gene_expression (producing) of stimulating hormone in pituitary associated with pituitary cancer and thyroid disease
10) Confidence 0.01 Published 2001 Journal Masui Section Abstract Doc Link 11244780 Disease Relevance 0.34 Pain Relevance 0.15
Thus naloxone (NAL), a specific opiate antagonist, has been shown to reduce basal serum levels of PRL and GH, and to elevate serum levels of LH and follicle stimulating hormone in male rats.
Gene_expression (levels) of stimulating hormone in follicle associated with antagonist, narcan and opiate
11) Confidence 0.00 Published 1980 Journal Fed. Proc. Section Abstract Doc Link 6247213 Disease Relevance 0.09 Pain Relevance 0.75

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