INT4495

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Context Info
Confidence 0.66
First Reported 1975
Last Reported 1995
Negated 0
Speculated 0
Reported most in Abstract
Documents 7
Total Number 7
Disease Relevance 2.43
Pain Relevance 2.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Adrb1) plasma membrane (Adrb1) nucleus (Adrb1)
cytoplasm (Adrb1) signal transducer activity (Adrb1)
Anatomy Link Frequency
uterine 1
heart 1
IPN 1
Adrb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 4 99.60 Very High Very High Very High
Angina 13 99.58 Very High Very High Very High
anesthesia 3 98.80 Very High Very High Very High
beta blocker 10 98.22 Very High Very High Very High
IPN 6 98.16 Very High Very High Very High
cva 3 97.42 Very High Very High Very High
Locus ceruleus 6 94.56 High High
ischemia 3 88.48 High High
adenocard 1 88.44 High High
Calcium channel 1 85.44 High High
Disease Link Frequency Relevance Heat
Cv General 3 Under Development 13 99.58 Very High Very High Very High
Coronary Artery Disease 6 99.40 Very High Very High Very High
Spontaneous Abortion 1 93.16 High High
Myocardial Infarction 3 92.96 High High
Angina 3 90.00 High High
Adverse Drug Reaction 1 88.60 High High
Heart Rate Under Development 3 83.80 Quite High
Hypotension 2 83.16 Quite High
Dysmenorrhea 2 82.64 Quite High
Arrhythmia Under Development 1 80.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Twenty-four patients with symptomatic stable effort angina despite full beta-blockade were randomized to a double-blind Latin square protocol in which they received propranolol in a dose producing full beta-receptor blockade, diltiazem, 240 mg/day, in divided doses and a combination of propranolol and diltiazem, 240 or 360 mg/day.
Gene_expression (producing) of beta-receptor associated with cva
1) Confidence 0.66 Published 1986 Journal J. Am. Coll. Cardiol. Section Abstract Doc Link 2868030 Disease Relevance 0.26 Pain Relevance 0.22
Quantitative radioautography indicated that beta 1-labeled binding sites account for the larger percentage of binding sites in the IPN.
Gene_expression (account) of beta 1-labeled in IPN associated with ipn
2) Confidence 0.59 Published 1989 Journal J. Neurosci. Section Abstract Doc Link 2568411 Disease Relevance 0 Pain Relevance 0.61
[The anesthesiological risk and treatment characteristics of patients with ischemic heart disease prepared preoperatively with beta-receptor blockers, calcium antagonists and nitro preparations].
Gene_expression (blockers) of beta-receptor in heart associated with anesthesia, coronary artery disease and antagonist
3) Confidence 0.58 Published 1993 Journal Khirurgiia (Sofiia) Section Title Doc Link 7983827 Disease Relevance 0.65 Pain Relevance 0.40
Celiprolol, a novel beta blocker, may be more effective than propranolol in unstable angina pectoris because of both its beta-1-receptor selectivity and its vasodilator property.
Gene_expression (selectivity) of beta-1-receptor associated with angina and beta blocker
4) Confidence 0.11 Published 1995 Journal Angiology Section Abstract Doc Link 7702198 Disease Relevance 0.58 Pain Relevance 0.64
In rabbits under pentobarbital anesthesia, infusion of flestolol (3.1, 10, and 31 micrograms/kg/min) produced dose-dependent beta-receptor blockade.
Gene_expression (produced) of beta-receptor associated with anesthesia
5) Confidence 0.08 Published 1987 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 2434798 Disease Relevance 0.37 Pain Relevance 0.18
The effect of the beta receptor stimulator, terbutaline, on uterine activity induced by intra-amniotic injection of prostaglandin F2alpha or hypertonic saline was investigated in 20 patients undergoing therapeutic abortion in the second trimester.
Gene_expression (effect) of beta receptor in uterine associated with spontaneous abortion
6) Confidence 0.08 Published 1975 Journal Br J Obstet Gynaecol Section Abstract Doc Link 1182093 Disease Relevance 0.18 Pain Relevance 0.08
The following properties of beta-blockers and the therapeutic relevance of these properties are to be discussed, together with pertinent examples of the drugs involved: beta 1-receptor selectivity and the degree of beta 2-receptor blockade; intrinsic sympathomimetic activity (ISA); duration of action (to be discussed in connection with the pharmacokinetic properties in Prof.
Gene_expression (selectivity) of beta 1-receptor associated with beta blocker
7) Confidence 0.06 Published 1990 Journal Clin Physiol Biochem Section Abstract Doc Link 1982758 Disease Relevance 0.40 Pain Relevance 0.16

General Comments

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