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Context Info
Confidence 0.47
First Reported 1983
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.91
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (CREG1) oxidoreductase activity (CREG1) extracellular region (CREG1)
transcription factor binding (CREG1)
Anatomy Link Frequency
internal 1
CREG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 96 96.76 Very High Very High Very High
chemokine 2 83.68 Quite High
cytokine 14 83.24 Quite High
spinal inflammation 1 75.00 Quite High
Inflammation 24 64.80 Quite High
cINOD 1 60.32 Quite High
methotrexate 1 57.36 Quite High
Osteoarthritis 48 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 96 96.76 Very High Very High Very High
Shock 1 92.28 High High
Genetic Translocation 1 83.28 Quite High
Syndrome 1 83.28 Quite High
Low Back Pain 1 75.00 Quite High
INFLAMMATION 24 64.80 Quite High
Disease 14 42.00 Quite Low
Hypersensitivity 2 36.24 Quite Low
Glioma 2 35.20 Quite Low
Down Syndrome 3 34.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Studies with larger numbers of B27 negative AS patients of various racial groups are needed to establish clearly if there is an association with B7-CREG antigens.
CREG Binding (association) of
1) Confidence 0.47 Published 1983 Journal Br. J. Rheumatol. Section Abstract Doc Link 6606463 Disease Relevance 0.16 Pain Relevance 0.07
Regarding internal molecular changes in the individuals, a participation of mutations or single nucleotide polymorphisms in different genes is plausible, either directly [45,46] or via mutated regulators (for example, transcription factors, mRNA stability modifiers, and so on [47]).
genes Binding (participation) of in internal
2) Confidence 0.02 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2575612 Disease Relevance 0.75 Pain Relevance 0.43

General Comments

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