INT45035

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Context Info
Confidence 0.16
First Reported 1983
Last Reported 1984
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.74
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (HLA-B, HLA-DRB4) endosome (HLA-DRB4) signal transduction (HLA-DRB4)
Golgi apparatus (HLA-DRB4) endoplasmic reticulum (HLA-DRB4)
HLA-B (Homo sapiens)
HLA-DRB4 (Homo sapiens)
Pain Link Frequency Relevance Heat
spinal inflammation 2 100.00 Very High Very High Very High
rheumatoid arthritis 1 99.80 Very High Very High Very High
Crohn's disease 5 99.26 Very High Very High Very High
Disease Link Frequency Relevance Heat
Low Back Pain 1 100.00 Very High Very High Very High
Rheumatoid Arthritis 2 99.80 Very High Very High Very High
Disease 8 99.26 Very High Very High Very High
Ankylosing Spondylitis 1 5.00 Very Low Very Low Very Low
Celiac Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the patients with Crohn's disease there was a strong association with HLA-DR4 and -DR5 (chi2 = 14 . 013, RR = 4 . 77 and chi2 = 9 . 345, RR = 5 . 04) and a weak association with HLA-Bw46 and -Bw51 (chi2 = 7 . 077, RR = 2 . 63, and chi2 = 5 . 401, RR = 2 . 52).
HLA-Bw46 Binding (association) of HLA-DR4 associated with crohn's disease and disease
1) Confidence 0.16 Published 1984 Journal J Clin Lab Immunol Section Abstract Doc Link 6611420 Disease Relevance 0.44 Pain Relevance 0.29
Measures of association for HLA-B27 and ankylosing spondylitis (AS) and HLA-DR4 and rheumatoid arthritis (RA) are calculated from previously published data.
HLA-B27 Binding (association) of HLA-DR4 associated with spinal inflammation and rheumatoid arthritis
2) Confidence 0.04 Published 1983 Journal J Rheumatol Suppl Section Abstract Doc Link 6607352 Disease Relevance 0.30 Pain Relevance 0.15

General Comments

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