INT45065

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Context Info
Confidence 0.54
First Reported 1983
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 6
Disease Relevance 2.34
Pain Relevance 1.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Ado) oxidoreductase activity (Ado)
Anatomy Link Frequency
blood 1
Ado (Mus musculus)
Pain Link Frequency Relevance Heat
adenocard 93 100.00 Very High Very High Very High
Analgesic 3 99.56 Very High Very High Very High
Potency 39 97.52 Very High Very High Very High
induced neuropathy 2 76.88 Quite High
Bioavailability 12 71.36 Quite High
Morphine 3 51.20 Quite High
Pain 1 43.76 Quite Low
antagonist 6 25.00 Low Low
Antinociceptive 3 25.00 Low Low
opioid receptor 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 189 100.00 Very High Very High Very High
Nociception 4 97.20 Very High Very High Very High
Death 1 80.84 Quite High
Paralysis 1 80.16 Quite High
Ataxia 1 79.60 Quite High
Neuropathic Pain 2 75.00 Quite High
Increased Venous Pressure Under Development 33 44.80 Quite Low
Pain 1 43.76 Quite Low
Stroke 12 34.04 Quite Low
Hypoxia 3 31.56 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study, the AK inhibitors 5'-amino,5'-deoxy-ADO (NH2dADO), 5-iodotubercidin (5-IT), and 5'-deoxy,5-iodotubercidin (5'd-5IT) were examined for their analgesic efficacy in the hot-plate model of acute somatic nociception.
Spec (examined) Gene_expression (examined) of ADO associated with nociception, adenocard and analgesic
1) Confidence 0.54 Published 1999 Journal Pharmacol. Biochem. Behav. Section Abstract Doc Link 10340527 Disease Relevance 0.26 Pain Relevance 0.47
In both fresh and pre-stored sections, ADO appeared to occur randomly, with different cells displaying dropout of the maternal or paternal allele (see example of ADO in Figure 2B).
Gene_expression (appeared) of ADO
2) Confidence 0.19 Published 2008 Journal BMC Biotechnol Section Body Doc Link PMC2266725 Disease Relevance 0 Pain Relevance 0
Ado Met levels in treated bats receiving pteroylmonoglutamic acid or methionine supplements were respectively 18 and 25% higher than in controls.
Gene_expression (levels) of Ado
3) Confidence 0.14 Published 1983 Journal Br. J. Nutr. Section Abstract Doc Link 6615764 Disease Relevance 0.32 Pain Relevance 0.15
Thus, the vasodilator potency was as follows: UTP control subjects (100) > ATP control subjects (55) > UTP diabetic subjects (47) > ATP diabetic subjects (29) > ADO control subjects (3) > ADO diabetic subjects (1.5).
Gene_expression (subjects) of ADO associated with adenocard, diabetes mellitus and potency
4) Confidence 0.11 Published 2010 Journal Diabetes Section Body Doc Link PMC2797920 Disease Relevance 0.67 Pain Relevance 0.37
Similarly, inhibition of both NO and PG synthesis during ADO infusion has been reported to reduce blood flow by ?
Gene_expression (infusion) of ADO in blood associated with adenocard
5) Confidence 0.11 Published 2010 Journal Diabetes Section Body Doc Link PMC2797920 Disease Relevance 0.42 Pain Relevance 0.20
Thus, the vasodilator potency was as follows: UTP control subjects (100) > ATP control subjects (55) > UTP diabetic subjects (47) > ATP diabetic subjects (29) > ADO control subjects (3) > ADO diabetic subjects (1.5).
Gene_expression (subjects) of ADO associated with adenocard, diabetes mellitus and potency
6) Confidence 0.11 Published 2010 Journal Diabetes Section Body Doc Link PMC2797920 Disease Relevance 0.67 Pain Relevance 0.37

General Comments

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