INT45100

Context Info Confidence 0.52 First Reported 1983 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 6 Total Number 6 Disease Relevance 2.04 Pain Relevance 0.17

cytosol (MYH9) ATPase activity (MYH9) plasma membrane (MYH9) nucleus (MYH9) protein complex (MYH9) cytoplasm (MYH9)

Anatomy Link Frequency PFO 1 MYH9 (Homo sapiens)

Pain Link Frequency Relevance Heat Chronic pancreatitis 2 98.24 headache 13 50.00 Migraine 9 50.00 ischemia 1 5.00 cva 1 5.00

Disease Link Frequency Relevance Heat Pancreatitis 12 98.76 Disease 4 96.56 Pressure And Volume Under Development 4 92.24 Epilepsy 9 88.44 Patent Foramen Ovale 10 87.84 Cv General 4 Under Development 1 84.84 Migraine Disorders 14 77.40 Stroke 2 50.00 Cv General 2 Under Development 1 5.00 Paradoxical Embolism 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Thirteen patients (34%) had a diagnosis of MHA made by the primary care physician or the referring neurologist.

Gene_expression (made) of MHA

1) Confidence 0.52 Published 2006 Journal Catheter Cardiovasc Interv Section Body Doc Link 16548006 Disease Relevance 0.08 Pain Relevance 0

RESULTS: Before the procedure, MHA was present in 24% of patients.

Gene_expression (present) of MHA

2) Confidence 0.52 Published 2008 Journal J Interv Cardiol Section Body Doc Link 18093099 Disease Relevance 0 Pain Relevance 0

Of the 131 patients, 35 (27%) had a diagnosis of MHA made by the primary care physician or the referring neurologist.

Gene_expression (made) of MHA

3) Confidence 0.50 Published 2006 Journal Am. Heart J. Section Body Doc Link 16569564 Disease Relevance 0.26 Pain Relevance 0

RESULTS: Before the procedure, MHA was present in 42% of patients (45% of patients with PFO and 30% of patients with ASD).

Gene_expression (present) of MHA in PFO

4) Confidence 0.37 Published 2005 Journal J. Am. Coll. Cardiol. Section Body Doc Link 15708691 Disease Relevance 0.15 Pain Relevance 0

There was no correlation between pathologically increased serum levels of enzyme activity and MHA.

Gene_expression (levels) of MHA

5) Confidence 0.30 Published 1983 Journal Leber Magen Darm Section Abstract Doc Link 6621243 Disease Relevance 0.78 Pain Relevance 0.10

MHA was positive in all cases with necrotizing pancreatitis, in all cases with a severe course of the disease involving circulatory insufficiency, and, with values significantly higher, in all cases with renal or pulmonary complications.

Gene_expression (positive) of MHA associated with pancreatitis and disease

6) Confidence 0.30 Published 1983 Journal Leber Magen Darm Section Abstract Doc Link 6621243 Disease Relevance 0.76 Pain Relevance 0.07

General Comments

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