INT45175

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Context Info
Confidence 0.56
First Reported 1983
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.46
Pain Relevance 1.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PTS) mitochondrion (PTS) small molecule metabolic process (PTS)
lyase activity (PTS) cellular amino acid metabolic process (PTS) cytoplasm (PTS)
Anatomy Link Frequency
muscles 1
PTS (Homo sapiens)
Pain Link Frequency Relevance Heat
Tetrahydrobiopterin 6 100.00 Very High Very High Very High
Pain 29 99.80 Very High Very High Very High
backache 52 99.70 Very High Very High Very High
Lasting pain 2 95.16 Very High Very High Very High
GCH1 2 82.48 Quite High
anesthesia 1 75.20 Quite High
depression 1 5.00 Very Low Very Low Very Low
central pain 1 5.00 Very Low Very Low Very Low
Sciatica 1 5.00 Very Low Very Low Very Low
biopsychosocial 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 28 99.80 Very High Very High Very High
Low Back Pain 53 99.70 Very High Very High Very High
Death 20 99.00 Very High Very High Very High
Injury 108 97.80 Very High Very High Very High
Neuropathic Pain 1 96.40 Very High Very High Very High
Liver Cancer 26 86.48 High High
Cancer 72 38.24 Quite Low
Stress 2 32.92 Quite Low
Fever 12 15.60 Low Low
Reprotox - General 1 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Heiss et al. [23], in a study in which 45 acute LBP patients were classified by four PTs who were unfamiliar with the classification system, found a low kappa value (0.15).
Gene_expression (classified) of PTs associated with backache
1) Confidence 0.56 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2859390 Disease Relevance 0.42 Pain Relevance 0.42
The features of PTS produced by the same type of noise was investigated in rabbits with and without functioning middle ear muscles.
Gene_expression (produced) of PTS in muscles
2) Confidence 0.52 Published 1983 Journal Acta Otolaryngol. Section Abstract Doc Link 6637452 Disease Relevance 0 Pain Relevance 0.08
All the cell samples reached the PTs in ?
Gene_expression (reached) of PTs
3) Confidence 0.43 Published 2006 Journal Ann Biomed Eng Section Body Doc Link PMC1705482 Disease Relevance 0.10 Pain Relevance 0
0.001%) was predicted for target PTs of 60–85°C and HRs of 5–600°C min?
Gene_expression (predicted) of PTs
4) Confidence 0.43 Published 2006 Journal Ann Biomed Eng Section Body Doc Link PMC1705482 Disease Relevance 0.41 Pain Relevance 0
The recently discovered link between tetrahydrobiopterin (BH4) synthesis and pain in preclinical models and humans provides a promising new approach for treating neuropathic and other forms of chronic pain.
Gene_expression (synthesis) of tetrahydrobiopterin associated with pain, tetrahydrobiopterin, lasting pain and neuropathic pain
5) Confidence 0.04 Published 2010 Journal Curr Opin Investig Drugs Section Abstract Doc Link 20047156 Disease Relevance 0.53 Pain Relevance 0.75

General Comments

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