INT45225

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Context Info
Confidence 0.53
First Reported 1983
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 5
Disease Relevance 2.79
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
smooth muscle cell 1
Hd (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 1 89.12 High High
Pain 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Renal Failure 432 100.00 Very High Very High Very High
Diabetes Mellitus 12 98.92 Very High Very High Very High
Fistula 4 69.36 Quite High
Chronic Renal Failure 24 43.80 Quite Low
Infection 4 33.80 Quite Low
Thrombosis 4 33.20 Quite Low
Renal Disease 20 32.20 Quite Low
Cardiovascular Disease 4 28.56 Quite Low
Disease 8 28.24 Quite Low
Peritonitis 8 27.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We studied rat aortic endothelial and smooth muscle cell de novo histamine synthesis mediated by histidine decarboxylase (HD) and the effects of its inhibition by alpha-hydrazinohistidine on the intracellular histamine content and intraaortic albumin accumulation in streptozotocin-induced diabetes.
Localization (accumulation) of HD in smooth muscle cell associated with diabetes mellitus
1) Confidence 0.53 Published 1983 Journal Arteriosclerosis Section Abstract Doc Link 6651615 Disease Relevance 0.61 Pain Relevance 0.09
Over the last few years a trend can be observed in a number of countries to increase the funding of HD services, especially satellite HD centres, which are smaller and often located closer to a patient's home.
Localization (located) of HD
2) Confidence 0.16 Published 2008 Journal Nephrology Dialysis Transplantation Section Body Doc Link PMC2441769 Disease Relevance 0.65 Pain Relevance 0
Patients who are employed have a greater tendency to select PD rather than HD; however, the choice of dialysis modality has not been proven to independently affect a patient's ability to maintain employment.
Localization (select) of HD associated with renal failure
3) Confidence 0.16 Published 2008 Journal Nephrology Dialysis Transplantation Section Body Doc Link PMC2441769 Disease Relevance 0.35 Pain Relevance 0
In Japan, reimbursement for HD is being decreased, and the Japanese Ministry of Health and Welfare is promoting home healthcare.
Localization (reimbursement) of HD
4) Confidence 0.16 Published 2008 Journal Nephrology Dialysis Transplantation Section Body Doc Link PMC2441769 Disease Relevance 0.82 Pain Relevance 0
When patients are either referred late to a nephrologist's care or must urgently initiate dialysis without a planned access, they are generally sicker, require longer hospitalization and are nearly always started on HD.
Localization (started) of HD
5) Confidence 0.16 Published 2008 Journal Nephrology Dialysis Transplantation Section Body Doc Link PMC2441769 Disease Relevance 0.36 Pain Relevance 0

General Comments

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