INT45272

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Context Info
Confidence 0.39
First Reported 1983
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 15
Total Number 16
Disease Relevance 8.08
Pain Relevance 2.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Nps) molecular_function (Nps)
Anatomy Link Frequency
neuronal 1
liver 1
projection neurons 1
pancreas 1
arms 1
Nps (Mus musculus)
Pain Link Frequency Relevance Heat
amygdala 303 100.00 Very High Very High Very High
Sciatica 7 99.92 Very High Very High Very High
positron emission tomography 11 99.90 Very High Very High Very High
Paracetamol 8 98.44 Very High Very High Very High
GABAergic 12 98.36 Very High Very High Very High
projection neuron 90 95.40 Very High Very High Very High
imagery 117 91.44 High High
Thalamus 1 82.12 Quite High
Neuropeptide 10 80.16 Quite High
Central nervous system 63 78.20 Quite High
Disease Link Frequency Relevance Heat
Syndrome 60 100.00 Very High Very High Very High
Open-angle Glaucoma 17 100.00 Very High Very High Very High
Nerve Root Compression 5 99.92 Very High Very High Very High
Glioblastoma 3 99.28 Very High Very High Very High
Pressure And Volume Under Development 38 99.16 Very High Very High Very High
Diabetes Mellitus 330 99.08 Very High Very High Very High
Injury 11 99.04 Very High Very High Very High
Cancer 108 99.00 Very High Very High Very High
Anxiety Disorder 144 98.92 Very High Very High Very High
Disease 44 90.84 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study we investigated the influence of NPs on the electrical activity changes in neuronal networks on MEA neurochips.
Spec (investigated) Regulation (influence) of NPs in neuronal
1) Confidence 0.39 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2957913 Disease Relevance 0.06 Pain Relevance 0.08
Here, no significant effect of NPS treatment was observed on anxiety-like behavior or exploratory activity, as time on open arms (F2.37?
Neg (no) Regulation (effect) of NPS in arms associated with anxiety disorder
2) Confidence 0.38 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2442874 Disease Relevance 0.55 Pain Relevance 0.03
Histological studies carried out over the liver and pancreas for the four groups i.e. control, diabetic control, diabetic control treated and gold treated exposed the capability of AuNPs in restoring the organs to normal histology in the diabetic treated mice in comparison to the morphological disruptions in the diabetic control mice.
Regulation (capability) of AuNPs in pancreas associated with diabetes mellitus
3) Confidence 0.33 Published 2010 Journal J Nanobiotechnology Section Body Doc Link PMC2914719 Disease Relevance 0.89 Pain Relevance 0.07
Several well-known NPS studies have reported cosegregation of OAG and NPS as a result of a pleiotropic effect of the LMX1B gene in different families [1-3,14].
Regulation (effect) of NPS associated with syndrome and open-angle glaucoma
4) Confidence 0.24 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2669506 Disease Relevance 1.44 Pain Relevance 0
These findings suggest that the normal daily changes in NPS levels may influence the lethality of acetaminophen.
Regulation (changes) of NPS associated with paracetamol
5) Confidence 0.24 Published 1983 Journal Toxicol. Appl. Pharmacol. Section Abstract Doc Link 6658786 Disease Relevance 0.13 Pain Relevance 0.65
Influence of Fe2O3 NPs on intracellular ROS formation
Regulation (Influence) of NPs
6) Confidence 0.23 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2957913 Disease Relevance 0 Pain Relevance 0
Influence of CB NPs on intracellular ROS formation
Regulation (Influence) of NPs
7) Confidence 0.23 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2957913 Disease Relevance 0.10 Pain Relevance 0
Excitation of the EPN is responsible for a modulation of BLA activity through NPS, characterized by a general increase of GABAergic inhibition and enhancement of spike activity in a subset of BLA projection neurons.
Regulation (modulation) of NPS in projection neurons associated with gabaergic, projection neuron and amygdala
8) Confidence 0.23 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2442874 Disease Relevance 0.25 Pain Relevance 0.40
Cut experiments reveal that input from the EPN is required for NPS modulation of GABAA-mediated feedback and feedforward inhibition in the BLA.
Regulation (modulation) of NPS associated with amygdala
9) Confidence 0.23 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2442874 Disease Relevance 0.38 Pain Relevance 0.20
In the present study the distribution of gold nanoparticles of 50 nm have been found, that particles do not to get accumulated in the kidney, stating that though these size ranges provide general clearance mechanisms, other physical parameters, clinical significance, and long-term persistence of gold nanoparticles simultaneously affecting NPs movement play a significant role in their distribution.
Regulation (affecting) of NPs in kidney
10) Confidence 0.20 Published 2010 Journal J Nanobiotechnology Section Body Doc Link PMC2914719 Disease Relevance 0.40 Pain Relevance 0.03
It is reported that hydrodynamic size [44] of nanoparticles (NPs) also affects NPs clearance from circulation [45-47].
Regulation (affects) of NPs
11) Confidence 0.20 Published 2010 Journal J Nanobiotechnology Section Body Doc Link PMC2914719 Disease Relevance 0 Pain Relevance 0
Effect of AgNPs on survival rate in DLA tumor-bearing mice
Regulation (Effect) of AgNPs associated with pressure and volume under development and cancer
12) Confidence 0.17 Published 2010 Journal Int J Nanomedicine Section Body Doc Link PMC2962271 Disease Relevance 1.47 Pain Relevance 0
Histological studies carried out over the liver and pancreas for the four groups i.e. control, diabetic control, diabetic control treated and gold treated exposed the capability of AuNPs in restoring the organs to normal histology in the diabetic treated mice in comparison to the morphological disruptions in the diabetic control mice.
Regulation (capability) of AuNPs in liver associated with diabetes mellitus
13) Confidence 0.11 Published 2010 Journal J Nanobiotechnology Section Body Doc Link PMC2914719 Disease Relevance 0.89 Pain Relevance 0.07
Plotkin et al. [187] employed PET for targeting the intra-tumourally injected magnetic NPs in patients with glioblastoma.
Regulation (targeting) of NPs associated with glioblastoma and positron emission tomography
14) Confidence 0.11 Published 2010 Journal Part Fibre Toxicol Section Body Doc Link PMC2847536 Disease Relevance 0.18 Pain Relevance 0.69
Sensitivity of MRI and NPS for diagnosing cervical radiculopathy was 93 and 42%, respectively.
Regulation (Sensitivity) of NPS associated with nerve root compression and sciatica
15) Confidence 0.07 Published 2002 Journal Br J Neurosurg Section Abstract Doc Link 12046733 Disease Relevance 0.36 Pain Relevance 0.47
NPs are very sensitive for primary or secondary cardiac dysfunction, but the specificity is low.
Regulation (sensitive) of NPs
16) Confidence 0.04 Published 2010 Journal Yonsei Medical Journal Section Body Doc Link PMC2824858 Disease Relevance 0.97 Pain Relevance 0

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