INT45303

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Context Info
Confidence 0.40
First Reported 1983
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 4
Total Number 6
Disease Relevance 2.14
Pain Relevance 3.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (SYNM) cytoplasm (SYNM)
SYNM (Homo sapiens)
Pain Link Frequency Relevance Heat
Fibrositis 111 100.00 Very High Very High Very High
Acute pain 3 99.84 Very High Very High Very High
Pain 48 99.74 Very High Very High Very High
opiate 5 99.08 Very High Very High Very High
Central nervous system 36 98.64 Very High Very High Very High
Gabapentin 72 96.64 Very High Very High Very High
Lasting pain 6 94.08 High High
positron emission tomography 11 91.96 High High
imagery 70 90.12 High High
agonist 1 75.92 Quite High
Disease Link Frequency Relevance Heat
Sleep Disorders 115 100.00 Very High Very High Very High
Pain 60 99.84 Very High Very High Very High
Congenital Anomalies 9 99.36 Very High Very High Very High
Cognitive Disorder 22 65.24 Quite High
Depression 9 55.92 Quite High
Persistent Vegetative State 70 5.00 Very Low Very Low Very Low
Brain Injury 24 5.00 Very Low Very Low Very Low
Diffuse Axonal Injury 10 5.00 Very Low Very Low Very Low
Handedness 4 5.00 Very Low Very Low Very Low
Coma 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although the mechanism by which it does so is unclear, pain is known to interact with the DMN.
DMN Binding (interact) of associated with pain
1) Confidence 0.40 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888218 Disease Relevance 0.69 Pain Relevance 0.66
The relevance of our finding about the syn-anti isomerism of the opiate hydrazones to the understanding of their interactions with the opiate receptor is discussed.
syn Spec (finding) Binding (finding) of associated with opiate
2) Confidence 0.36 Published 1983 Journal Life Sci. Section Abstract Doc Link 6664221 Disease Relevance 0 Pain Relevance 0.53
Further studies yielding fMRI and connectivity data will be needed to clarify the association between pathogenesis of FM and DMN.


DMN Binding (association) of associated with fibrositis
3) Confidence 0.30 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888218 Disease Relevance 0.64 Pain Relevance 0.91
The present study showed significant hyperperfusion in areas associated with the DMN in addition to abnormalities in the sensory dimension of pain processing and affective-attentional areas in patients with FM.
DMN Binding (associated) of associated with pain, congenital anomalies and fibrositis
4) Confidence 0.30 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2888218 Disease Relevance 0.70 Pain Relevance 0.98
A 'resting state' functional connectivity analysis was also performed in order to further characterize the DMN in this patient.
DMN Binding (characterize) of
5) Confidence 0.23 Published 2010 Journal BMC Neurol Section Body Doc Link PMC2941677 Disease Relevance 0.07 Pain Relevance 0
The analysis of task-related deactivations allows the identification of regions considered to be associated with the DMN [34].
DMN Binding (associated) of
6) Confidence 0.22 Published 2010 Journal BMC Neurol Section Body Doc Link PMC2941677 Disease Relevance 0.05 Pain Relevance 0

General Comments

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