INT45316

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.39
First Reported 1983
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.63
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Icam5)
Icam5 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 7 71.72 Quite High
Hippocampus 48 57.84 Quite High
Potency 6 51.84 Quite High
Sciatic nerve 1 50.00 Quite Low
Central nervous system 8 5.00 Very Low Very Low Very Low
Substantia nigra 8 5.00 Very Low Very Low Very Low
antiepileptic Drug 4 5.00 Very Low Very Low Very Low
antidepressant 4 5.00 Very Low Very Low Very Low
isoflurane 4 5.00 Very Low Very Low Very Low
local anesthetic 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Convulsion 348 97.36 Very High Very High Very High
Unconsciousness 1 81.00 Quite High
Sprains And Strains 6 64.08 Quite High
Attention Deficit Hyperactivity Disorder 2 20.08 Low Low
Death 14 5.00 Very Low Very Low Very Low
Epilepsy 14 5.00 Very Low Very Low Very Low
Body Weight 12 5.00 Very Low Very Low Very Low
Injury 10 5.00 Very Low Very Low Very Low
Lymphatic Filariasis 10 5.00 Very Low Very Low Very Low
Brain Injury 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, the addition of stroboscopic light stimulation (1-100 Hz) to the above procedure (doses 17.5 to 30 mg/kg) reduced the CD50 for the IC rats but did not affect the CD50 for the EC rats.
Neg (not) Regulation (affect) of CD50
1) Confidence 0.39 Published 1983 Journal Physiol. Behav. Section Abstract Doc Link 6665059 Disease Relevance 0.24 Pain Relevance 0.07
The CD50 values obtained for the two treatments were not statistically significantly different.


Regulation (values) of CD50
2) Confidence 0.15 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2695230 Disease Relevance 0.82 Pain Relevance 0
The demonstration of dose-dependent convulsions in the dosage range 100–150 mg/kg in this study is consistent with the results of previous studies in mice.7,8,30 In addition, the CD50 values of 103 and 110 mg/kg obtained in this study for bupropion HCl and bupropion HBr treatments, respectively, are similar to the values of 116.72 (CI: 107.95, 126.20) and 119.7 (CI: 104.1, 137.6) mg/kg reported previously for IP bupropion HCl administration in mice.7,30
Regulation (values) of CD50 associated with convulsion
3) Confidence 0.15 Published 2009 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2695230 Disease Relevance 0.57 Pain Relevance 0.05
CONCLUSIONS: More pronounced analgesic effects obtained by complexation with HPb-CD have shown that both formulations, S50-R50HPb-CD and S75-R25HPb-CD, are very useful for postoperative pain relief, requiring lower LA concentrations.
Regulation (useful) of S50-R50HPb-CD
4) Confidence 0.02 Published 2005 Journal Rev Bras Anestesiol Section Body Doc Link 19471836 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox