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Context Info
Confidence 0.04
First Reported 1983
Last Reported 1999
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.12
Pain Relevance 0.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IGF1, GH1) extracellular region (IGF1, GH1) signal transduction (IGF1)
IGF1 (Homo sapiens)
GH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Fibrositis 14 93.84 High High
anesthesia 1 91.92 High High
Intracerebroventricular 1 88.56 High High
Pain 2 81.72 Quite High
Disease Link Frequency Relevance Heat
Fibromyalgia 13 93.84 High High
Syndrome 2 89.88 High High
Fatigue 2 82.16 Quite High
Pain 1 81.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To gain further insight into the mechanisms leading to dysregulation of the GH-IGF-1 axis in these patients, we assessed 24-h spontaneous GH secretion, GH responses to GHRH, and IGF-1 and IGF binding protein (BP)-3 levels before and after 4 days treatment with human (h)GH.
IGF-1 Regulation (responses) of GH
1) Confidence 0.04 Published 1999 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 10487713 Disease Relevance 1.12 Pain Relevance 0.51
To investigate the feedback control of GH secretion, we examined the effects of human GH (hGH) and somatomedin C (SmC) on spontaneous GH secretory surges in unanesthetized, freely moving rats.
somatomedin C Spec (examined) Regulation (effects) of hGH
2) Confidence 0.03 Published 1983 Journal Endocrinology Section Abstract Doc Link 6684547 Disease Relevance 0 Pain Relevance 0.14

General Comments

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