INT45395

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Context Info
Confidence 0.73
First Reported 1983
Last Reported 2005
Negated 0
Speculated 0
Reported most in Title
Documents 2
Total Number 2
Disease Relevance 0.40
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (CHRM1) signal transduction (CHRM1) protein modification process (CHRM1)
plasma membrane (CHRM1) signal transducer activity (CHRM1)
Anatomy Link Frequency
M-1 1
CHRM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Clonidine 2 100.00 Very High Very High Very High
antagonist 2 89.92 High High
Dopamine 1 87.76 High High
Pain 1 83.04 Quite High
Disease Link Frequency Relevance Heat
Myalgia 1 83.04 Quite High
Muscle Weakness 1 82.40 Quite High
Rhabdomyolysis 3 82.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cerivastatin is catabolized by cytochrome P450, 3A4 and 2C8 to M-1, and by 2C8 to M-23.
Localization (catabolized) of M-1 in M-1
1) Confidence 0.73 Published 2005 Journal J Clin Pharm Ther Section Abstract Doc Link 15811174 Disease Relevance 0.40 Pain Relevance 0.08
Cholinergic receptor control mechanisms for L-dopa, apomorphine, and clonidine-induced growth hormone secretion in man.
Localization (secretion) of Cholinergic receptor associated with clonidine
2) Confidence 0.41 Published 1983 Journal J. Clin. Endocrinol. Metab. Section Title Doc Link 6688812 Disease Relevance 0 Pain Relevance 0.32

General Comments

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