INT45489

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Context Info
Confidence 0.77
First Reported 1984
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 3.29
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (SRF) nucleolus (SRF) nucleus (SRF)
transcription factor binding (SRF) cytoplasm (SRF)
Anatomy Link Frequency
nodules 1
SRF (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 3 93.96 High High
Snapping jaw 5 88.72 High High
headache 1 80.56 Quite High
tolerance 1 75.00 Quite High
Rheumatism 1 75.00 Quite High
rheumatoid arthritis 2 50.00 Quite Low
Pain 2 10.00 Low Low
Angina 10 5.00 Very Low Very Low Very Low
Inflammation 8 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Psoriasis 2 97.44 Very High Very High Very High
Cancer 37 96.12 Very High Very High Very High
Arthritis 2 93.96 High High
Seronegative Spondarthritis 1 91.36 High High
Toxicity 1 89.28 High High
Ankylosis 4 89.12 High High
Temporomandibular Joint Syndrome 5 88.72 High High
Disorder Of Lipid Metabolism 12 88.32 High High
Breast Cancer 12 86.96 High High
Thrombocytopenia 1 86.88 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Serum rheumatoid factor was not detected.
Neg (not) Gene_expression (detected) of Serum rheumatoid factor
1) Confidence 0.77 Published 2005 Journal Rev Med Chir Soc Med Nat Iasi Section Abstract Doc Link 16607767 Disease Relevance 1.26 Pain Relevance 0.59
Tumors in the high SMC serum-response group were associated with poorer overall survival (p = 0.001) (Figure 5C) than those in the low SMC serum-response group, confirming the prognostic value of the serum-response gene expression program of vascular SMCs.
Gene_expression (expression) of serum-response gene associated with cancer
2) Confidence 0.63 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1994710 Disease Relevance 0.71 Pain Relevance 0
One model was developed using RBC-FAs(FA), another with the 7 standard risk factors (SRF), and another using the FAs selected in the FA model combined with the standard risk factors (SRF+FA).
Gene_expression (using) of SRF
3) Confidence 0.60 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2673680 Disease Relevance 0.16 Pain Relevance 0
In addition to using the stepwise selected FAs, four pre-specified FA metrics were also tested for their ability to add to the SRF model: the omega-3 index (eicosapentaenoic acid (EPA)+docosahexaenoic acid (DHA)) [21], the n-6?
Gene_expression (model) of SRF
4) Confidence 0.60 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2673680 Disease Relevance 0.14 Pain Relevance 0
No neutralizing INF alpha 2 serum factor was detected during the treatment.
Gene_expression (detected) of INF alpha 2 serum factor
5) Confidence 0.42 Published 1984 Journal Bull Cancer Section Abstract Doc Link 6713113 Disease Relevance 0.89 Pain Relevance 0.12
Of those, 2/3 were female, 6% (1/18) had subcutaneous nodules, 7% (1/14) had elevated levels of serum rheumatoid factor, and 44% (7/16) had elevated serum levels of antinuclear antibodies.
Gene_expression (levels) of serum rheumatoid factor in nodules
6) Confidence 0.01 Published 2002 Journal J. Rheumatol. Section Body Doc Link 12375336 Disease Relevance 0.13 Pain Relevance 0

General Comments

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