INT45666

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.50
First Reported 1982
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 7
Disease Relevance 3.12
Pain Relevance 1.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IFNB1) extracellular region (IFNB1)
IFNB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Multiple sclerosis 38 99.40 Very High Very High Very High
imagery 112 95.16 Very High Very High Very High
corticosteroid 1 87.16 High High
Inflammation 4 85.96 High High
intrathecal 3 75.00 Quite High
abdominal pain 1 63.56 Quite High
headache 3 55.16 Quite High
Angina 3 40.80 Quite Low
Pain 11 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Demyelinating Disease 38 99.40 Very High Very High Very High
Inflammatory Bowel Disease 5 99.08 Very High Very High Very High
Disease 16 94.64 High High
Lumbar Puncture Related Headaches 1 94.64 High High
Chronic Disease 1 89.56 High High
INFLAMMATION 3 85.96 High High
Sprains And Strains 2 75.40 Quite High
Mucositis 1 74.08 Quite High
Fever 3 63.96 Quite High
Abdominal Pain 1 63.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Their clinical courses were compared with those of ten MS control patients who did not receive IFN-beta.
Neg (not) Positive_regulation (receive) of IFN-beta associated with multiple sclerosis
1) Confidence 0.50 Published 1982 Journal Arch. Neurol. Section Abstract Doc Link 6751302 Disease Relevance 0.53 Pain Relevance 0.22
Biological agents such as beta-Interferon seem to be effective in mild to moderately ulcerative colitis, but further studies have to be performed.
Positive_regulation (effective) of beta-Interferon associated with inflammatory bowel disease
2) Confidence 0.46 Published 2004 Journal Langenbecks Arch Surg Section Abstract Doc Link 15133672 Disease Relevance 1.18 Pain Relevance 0.25
As is the case with other HTs, one interviewee related the increasing use of interferon beta to advertising by pharmaceutical companies.
Positive_regulation (increasing) of interferon beta
3) Confidence 0.33 Published 2010 Journal Health Res Policy Syst Section Body Doc Link PMC2907640 Disease Relevance 0.23 Pain Relevance 0.16
Other factors for increased interferon beta use mentioned by interviewees were the increasing number of MS patients, incremental consumption of the drug even in cases without indication, and government subsidies making it affordable for more MS patients.
Positive_regulation (increased) of interferon beta associated with multiple sclerosis
4) Confidence 0.33 Published 2010 Journal Health Res Policy Syst Section Body Doc Link PMC2907640 Disease Relevance 0.27 Pain Relevance 0.18
Two interviewees stated that this use is not proportional to the expected increase in MS patients as there has been a 10-fold increase in interferon beta use over the past six years.
Positive_regulation (increase) of interferon beta associated with multiple sclerosis
5) Confidence 0.33 Published 2010 Journal Health Res Policy Syst Section Body Doc Link PMC2907640 Disease Relevance 0.22 Pain Relevance 0.15
Other factors for increased interferon beta use mentioned by interviewees were the increasing number of MS patients, incremental consumption of the drug even in cases without indication, and government subsidies making it affordable for more MS patients.
Positive_regulation (increased) of interferon beta associated with multiple sclerosis
6) Confidence 0.24 Published 2010 Journal Health Res Policy Syst Section Body Doc Link PMC2907640 Disease Relevance 0.27 Pain Relevance 0.18
In that sense, some examples exist already in the market such as different insulins, somatotrophins, and CHO cells-derived interferon beta from different manufacturing sites [41].
Positive_regulation (derived) of interferon beta
7) Confidence 0.04 Published 2005 Journal BMC Nephrol Section Body Doc Link PMC1164417 Disease Relevance 0.41 Pain Relevance 0.06

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox