INT45730

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Context Info
Confidence 0.68
First Reported 1980
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 2.40
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PAH) small molecule metabolic process (PAH) cellular nitrogen compound metabolic process (PAH)
Anatomy Link Frequency
spina 1
PAH (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 2 99.64 Very High Very High Very High
agonist 5 97.04 Very High Very High Very High
drug abuse 1 91.80 High High
alcohol 3 91.20 High High
Pain 2 65.12 Quite High
Inflammation 18 51.72 Quite High
Catecholamine 30 21.36 Low Low
imagery 12 5.00 Very Low Very Low Very Low
noradrenaline 4 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pheochromocytoma 50 100.00 Very High Very High Very High
Phenylketonuria 1 100.00 Very High Very High Very High
Paraganglioma 48 99.80 Very High Very High Very High
Cretinism 1 99.80 Very High Very High Very High
Spina Bifida Cystica 1 97.80 Very High Very High Very High
Communicable Diseases 1 96.88 Very High Very High Very High
Hypertension 15 95.96 Very High Very High Very High
Nicotine Addiction 1 92.16 High High
Drug Dependence 1 91.80 High High
Necrosis 14 91.08 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Screening includes programs for the detection of PKU and congenital hypothyroidism in newborn infants, for spina bifida cystica in the unborn fetus, and hypertension.
Transcription (detection) of PKU in spina associated with spina bifida cystica, phenylketonuria, hypertension and cretinism
1) Confidence 0.68 Published 1980 Journal Med Care Section Abstract Doc Link 6772886 Disease Relevance 0.67 Pain Relevance 0.16
As the majority of PH and PGL secrete predominantly the ?
Transcription (majority) of PH associated with paraganglioma and pheochromocytoma
2) Confidence 0.31 Published 2006 Journal Orphanet J Rare Dis Section Body Doc Link PMC1702343 Disease Relevance 1.34 Pain Relevance 0.15
VLCAD, PH, and PT mRNA levels were significantly lower in Ppar?
Transcription (levels) of PH
3) Confidence 0.05 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2974693 Disease Relevance 0.31 Pain Relevance 0.03
by TRI exposure and more-pronounced increases in PH protein and VLCAD mRNA expression and ALT and AST levels in response to TRI exposure in our previous study using cyp2e1+/+ mice.
Transcription (expression) of PH
4) Confidence 0.04 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2974693 Disease Relevance 0.07 Pain Relevance 0

General Comments

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