INT4588

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Context Info
Confidence 0.47
First Reported 1975
Last Reported 1989
Negated 2
Speculated 0
Reported most in Abstract
Documents 4
Total Number 5
Disease Relevance 1.24
Pain Relevance 2.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Ren) extracellular space (Ren) extracellular region (Ren)
intracellular (Ren) response to stress (Ren)
Anatomy Link Frequency
plasma 8
Ren (Rattus norvegicus)
Pain Link Frequency Relevance Heat
anesthesia 13 100.00 Very High Very High Very High
epidural 10 100.00 Very High Very High Very High
Catecholamine 6 100.00 Very High Very High Very High
narcan 9 99.98 Very High Very High Very High
dexamethasone 3 93.76 High High
antagonist 1 86.96 High High
opiate 1 86.16 High High
analgesia 2 80.40 Quite High
Opioid 1 37.36 Quite Low
Disease Link Frequency Relevance Heat
Hyperaldosteronism 9 99.60 Very High Very High Very High
Adenoma 5 99.44 Very High Very High Very High
Hypercapnia 1 96.76 Very High Very High Very High
Hypoxia 2 95.68 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The infusion of endothelin into the renal artery of anesthetized rats at 1 ng/kg per min, a dose with no influence on renal function, had no effect on the basal levels of plasma renin activity (PRA) and renin secretory rate (RSR), but significantly inhibited the isoproterenol-induced increases in PRA and RSR.
Neg (no) Positive_regulation (effect) of Neg (no) Regulation (effect) of renin in plasma
1) Confidence 0.47 Published 1989 Journal Eur. J. Pharmacol. Section Abstract Doc Link 2680527 Disease Relevance 0 Pain Relevance 0
Effects of epidural anesthesia on catecholamines, renin activity, and vasopressin changes induced by tilt in elderly men.
Positive_regulation (induced) of Regulation (Effects) of renin associated with anesthesia, catecholamine and epidural
2) Confidence 0.27 Published 1985 Journal Anesthesiology Section Title Doc Link 3883849 Disease Relevance 0 Pain Relevance 0.88
Posttilt plasma renin activity values at 5 and 15 min were increased significantly when compared with the preepidural values (2,752 +/- 1,168, 2,410 +/- 1,214 and 713 +/- 190 pg X ml-1 X h-1, respectively).
Positive_regulation (increased) of Regulation (values) of renin in plasma
3) Confidence 0.25 Published 1985 Journal Anesthesiology Section Abstract Doc Link 3883849 Disease Relevance 0 Pain Relevance 0.65
[Proceedings: Experimentally induced effects on the plasma renin activity].
Positive_regulation (induced) of Regulation (effects) of renin in plasma associated with anesthesia
4) Confidence 0.10 Published 1975 Journal Schweiz Med Wochenschr Section Title Doc Link 1215977 Disease Relevance 0.29 Pain Relevance 0.20
In normals as well as in APA and IHA patients, naloxone caused a significant increase in plasma cortisol, and no change in ACTH, plasma renin activity (PRA) and aldosterone levels.
Positive_regulation (caused) of Neg (no) Regulation (change) of renin in plasma associated with adenoma, hyperaldosteronism and narcan
5) Confidence 0.03 Published 1988 Journal J. Endocrinol. Invest. Section Abstract Doc Link 2970500 Disease Relevance 0.95 Pain Relevance 0.53

General Comments

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