INT45898

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Context Info
Confidence 0.25
First Reported 1982
Last Reported 1982
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.32
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (LGR6) signal transducer activity (LGR6)
LGR6 (Homo sapiens)
Pain Link Frequency Relevance Heat
opiate 7 99.12 Very High Very High Very High
narcan 5 79.88 Quite High
antagonist 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Syndrome 3 95.74 Very High Very High Very High
Hypopituitarism 3 94.84 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These observations suggest that: 1) endogenous opiate mechanisms are unlikely to constitute a principal factor in maintaining hypogonadotropism in idiopathic hypopituitarism, delayed adolescence, or Kallmann's syndrome, at least acutely; 2) endogenous opiate mechanisms also cannot be implicated in the acute regulation or PRL secretion in children; and 3) the capability of adult men, but not early pubertal boys, to respond with increased gonadotropin secretion during inhibition of opiate receptors suggests that maturation of the opiate-related neuroendocrine system occurs during the course of sexual development in the human.
Positive_regulation (increased) of Localization (secretion) of gonadotropin associated with syndrome, opiate and hypopituitarism
1) Confidence 0.25 Published 1982 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 6809778 Disease Relevance 0.32 Pain Relevance 0.63

General Comments

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