INT45913

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Context Info
Confidence 0.40
First Reported 1982
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 5.27
Pain Relevance 0.83

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Apcs) extracellular region (Apcs) protein complex assembly (Apcs)
protein complex (Apcs)
Apcs (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammatory mediators 38 100.00 Very High Very High Very High
dexamethasone 82 98.64 Very High Very High Very High
rheumatoid arthritis 1 86.80 High High
abdominal pain 1 85.64 High High
spinal inflammation 1 84.80 Quite High
Inflammation 30 52.88 Quite High
cytokine 6 24.32 Low Low
Bile 13 5.00 Very Low Very Low Very Low
medulla 12 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatitis 118 100.00 Very High Very High Very High
Obstructive Jaundice 37 100.00 Very High Very High Very High
Alzheimer's Dementia 2 100.00 Very High Very High Very High
Macroglobulinemia 2 100.00 Very High Very High Very High
INFLAMMATION 76 99.98 Very High Very High Very High
Apoptosis 111 99.68 Very High Very High Very High
Multiple Myeloma 2 95.68 Very High Very High Very High
Injury 14 87.36 High High
Rheumatoid Arthritis 1 86.80 High High
Abdominal Pain 1 85.64 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In our previous reports, we have detected the serum contents of some inflammatory mediators in SAP and OJ rats (including endotoxin, PLA2, and TNF-?)
Positive_regulation (mediators) of Gene_expression (rats) of SAP associated with inflammatory mediators, pancreatitis and obstructive jaundice
1) Confidence 0.40 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2822241 Disease Relevance 1.52 Pain Relevance 0.23
Serum amyloid P-component (protein SAP) levels in patients with Waldenström's macroglobulinaemia have been determined to be markedly elevated (83 +/- 34 micrograms/ml) compared with healthy adult controls (35 +/- 11 micrograms/ml) and patients with multiple myeloma (39 +/- 17 micrograms/ml).
Spec (determined) Positive_regulation (elevated) of Gene_expression (levels) of Serum amyloid P-component associated with macroglobulinemia, alzheimer's dementia and multiple myeloma
2) Confidence 0.30 Published 1982 Journal J Clin Lab Immunol Section Abstract Doc Link 6813503 Disease Relevance 0.84 Pain Relevance 0.13
be relevant to expression of Caspase-3 protein in SAP.
Positive_regulation (relevant) of Gene_expression (expression) of SAP associated with pancreatitis
3) Confidence 0.25 Published 2007 Journal Mediators of Inflammation Section Body Doc Link PMC2234334 Disease Relevance 1.48 Pain Relevance 0.16
We have found in practice [38] that ideal SAP rat models can be induced by
Positive_regulation (induced) of Gene_expression (models) of SAP associated with pancreatitis
4) Confidence 0.22 Published 2007 Journal Mediators of Inflammation Section Body Doc Link PMC2234334 Disease Relevance 1.43 Pain Relevance 0.31

General Comments

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