INT4597

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Context Info
Confidence 0.39
First Reported 1975
Last Reported 2010
Negated 1
Speculated 3
Reported most in Abstract
Documents 5
Total Number 8
Disease Relevance 2.25
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (SCD) endoplasmic reticulum (SCD)
Anatomy Link Frequency
eye 1
gonadal 1
SCD (Homo sapiens)
Pain Link Frequency Relevance Heat
Neuropeptide 1 97.60 Very High Very High Very High
tolerance 3 96.28 Very High Very High Very High
Pain 15 87.76 High High
Cannabinoid 5 86.48 High High
Morphine 2 76.16 Quite High
agonist 1 65.52 Quite High
ischemia 6 42.56 Quite Low
Enkephalin 2 25.00 Low Low
Opioid 1 25.00 Low Low
Potency 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Myocardial Infarction 48 100.00 Very High Very High Very High
Sickle Cell Anemia 12 100.00 Very High Very High Very High
Myelodysplastic Syndromes 19 99.70 Very High Very High Very High
Thalassemia 28 99.40 Very High Very High Very High
Heart Rate Under Development 4 98.48 Very High Very High Very High
Hyperlipidemia 2 93.76 High High
Pain 10 87.76 High High
Sudden Death 22 84.64 Quite High
Genu Valgum 1 80.40 Quite High
Anaemia 25 71.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Men and women were compared, using analysis of covariance (ANCOVA), controlling for age, SCD genotype, depression, and education.
Regulation (controlling) of SCD
1) Confidence 0.39 Published 2006 Journal J Womens Health (Larchmt) Section Body Doc Link 16536678 Disease Relevance 0.21 Pain Relevance 0
When combined, no change of the delta9-THC effect occurred.
Neg (no) Regulation (change) of delta9-THC
2) Confidence 0.21 Published 1975 Journal Pharmacology Section Abstract Doc Link 1221432 Disease Relevance 0.30 Pain Relevance 0.09
Considering the importance of SCD in athletes and the requisite for an update of this matter, we endeavored to describe SCD in athletes.
Regulation (importance) of SCD associated with myocardial infarction
3) Confidence 0.16 Published 2010 Journal Sports Med Arthrosc Rehabil Ther Technol Section Abstract Doc Link PMC2923123 Disease Relevance 0.82 Pain Relevance 0
These findings demonstrate that marijuana use history may affect the subjective effects of oral delta9-THC, but that the influence of drug use history depends on the dose of drug administered.
Spec (may) Regulation (affect) of delta9-THC
4) Confidence 0.12 Published 1999 Journal Pharmacol. Biochem. Behav. Section Abstract Doc Link 10340534 Disease Relevance 0 Pain Relevance 0.22
-thalassemia (n = 274), MDS (n = 168) and SCD (n = 50) who were enrolled in the EPIC study.82


Regulation (enrolled) of SCD associated with sickle cell anemia, thalassemia and myelodysplastic syndromes
5) Confidence 0.07 Published 2009 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2773754 Disease Relevance 0.76 Pain Relevance 0
Generalization tests with 18 mg/kg (R)-methanandamide yielded around 90% delta9-THC responses in the two lower delta9-THC training dose conditions.
Regulation (responses) of delta9-THC
6) Confidence 0.07 Published 1998 Journal Psychopharmacology (Berl.) Section Abstract Doc Link 9888629 Disease Relevance 0 Pain Relevance 0.14
SCD is usually bilateral, but one eye may become affected prior to the other.
Spec (may) Regulation (affected) of SCD in eye
7) Confidence 0.03 Published 2009 Journal Orphanet J Rare Dis Section Body Doc Link PMC2695576 Disease Relevance 0.17 Pain Relevance 0
However, whether gonadal steroids regulate delta9-THC effects on PENK gene expression in the hypothalamus of male and female rats remains unknown.
Spec (whether) Regulation (regulate) of delta9-THC in gonadal
8) Confidence 0.00 Published 2002 Journal J. Psychopharmacol. (Oxford) Section Abstract Doc Link 12503826 Disease Relevance 0 Pain Relevance 0.05

General Comments

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