INT46152

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Context Info
Confidence 0.46
First Reported 1983
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 8
Disease Relevance 4.05
Pain Relevance 5.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (CYP4F22)
CYP4F22 (Homo sapiens)
Pain Link Frequency Relevance Heat
Acupuncture 448 100.00 Very High Very High Very High
analgesia 18 99.62 Very High Very High Very High
electroacupuncture 91 99.52 Very High Very High Very High
Pain 167 99.00 Very High Very High Very High
colic 66 98.60 Very High Very High Very High
narcan 5 98.28 Very High Very High Very High
Visceral pain 2 97.08 Very High Very High Very High
Pain threshold 1 95.36 Very High Very High Very High
depression 3 94.00 High High
anesthesia 2 90.64 High High
Disease Link Frequency Relevance Heat
Pain 173 99.00 Very High Very High Very High
Increased Venous Pressure Under Development 20 98.72 Very High Very High Very High
Abdominal Cramps 66 98.60 Very High Very High Very High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super / Visceral Pain

2 97.08 Very High Very High Very High
Hypesthesia 32 95.20 Very High Very High Very High
Depression 3 94.00 High High
Eczema 2 87.20 High High
Exanthema 2 86.40 High High
Dyspepsia 17 79.44 Quite High
Anxiety Disorder 2 76.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To minimize the influence of exogenous factors, 13 volunteers were anesthetized with sevoflurane 1 MAC while exposed to manual acupuncture stimulation of LI-4 (Group 1, n = 7) or a placebo point in the space between the third and fourth metacarpals (Group II, n = 6).
Positive_regulation (stimulation) of LI-4 associated with acupuncture
1) Confidence 0.46 Published 2007 Journal Anesth. Analg. Section Abstract Doc Link 17242085 Disease Relevance 0 Pain Relevance 0.37
Subjects who demonstrated acupunctural analgesia during electrical stimulation of the LI-4 point on the hands received either 1.2 mg naloxone or normal saline under double blind conditions.
Positive_regulation (stimulation) of LI-4 associated with narcan and analgesia
2) Confidence 0.46 Published 1983 Journal Pain Section Abstract Doc Link 6866539 Disease Relevance 0.31 Pain Relevance 1.02
Both EA and Ls groups received stimulation of the points Ho-ku (LI-4) and Tzu-San-Li (ST-36).
Positive_regulation (stimulation) of LI-4 associated with electroacupuncture
3) Confidence 0.45 Published 1997 Journal Am. J. Chin. Med. Section Abstract Doc Link 9358899 Disease Relevance 0 Pain Relevance 0.44
Identical genuine or sham EA was performed by a licensed acupuncturist at acupoints LI3 and LI4 on the right hand during Sessions 2 and 3.
Positive_regulation (acupoints) of LI3 associated with electroacupuncture
4) Confidence 0.16 Published 2010 Journal Mol Pain Section Body Doc Link PMC2993660 Disease Relevance 0.25 Pain Relevance 0.66
Many sensations were shared by the deqi response generated at LI4, ST36 and LV3, but more careful examination of the data revealed differences in frequency, intensity and in the weights and rank ordering of individual sensations facilitated by the deqi composite.
Positive_regulation (generated) of LI4
5) Confidence 0.04 Published 2007 Journal BMC Complement Altern Med Section Body Doc Link PMC2200650 Disease Relevance 1.02 Pain Relevance 1.39
Aching, soreness, warmth and dull pain were significantly more frequent than in tactile stimulation for LI4; aching, soreness, pressure and dull pain showed significant differences for ST36; aching, soreness, pressure, warmth, numbness and tingling all showed differences for LV3 (Table 3).
Positive_regulation (stimulation) of LI4 associated with pain, hypesthesia and increased venous pressure under development
6) Confidence 0.03 Published 2007 Journal BMC Complement Altern Med Section Body Doc Link PMC2200650 Disease Relevance 1.12 Pain Relevance 0.73
Thus it is plausible that even modest stimulation of LI4, as performed in this study, can influence either or both mechanisms and thereby alleviate infantile colic.


Positive_regulation (stimulation) of LI4 associated with colic
7) Confidence 0.03 Published 2010 Journal Acupuncture in Medicine Section Body Doc Link PMC3002757 Disease Relevance 0.59 Pain Relevance 0.53
Standardised, light stimulation of the acupuncture point LI4 twice a week for 3 weeks reduced the duration and intensity of crying more quickly in the acupuncture group than in the control group.
Positive_regulation (stimulation) of LI4 associated with acupuncture
8) Confidence 0.03 Published 2010 Journal Acupuncture in Medicine Section Body Doc Link PMC3002757 Disease Relevance 0.66 Pain Relevance 0.41

General Comments

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