INT46160

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Context Info
Confidence 0.53
First Reported 1983
Last Reported 2009
Negated 1
Speculated 2
Reported most in Body
Documents 4
Total Number 6
Disease Relevance 0.99
Pain Relevance 2.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transport (AVP) cell-cell signaling (AVP) response to stress (AVP)
signal transducer activity (AVP) cytosol (AVP) extracellular space (AVP)
Anatomy Link Frequency
plasma 6
AVP (Homo sapiens)
Pain Link Frequency Relevance Heat
epidural 10 100.00 Very High Very High Very High
Endogenous opioid 4 99.60 Very High Very High Very High
Perioperative pain 6 97.04 Very High Very High Very High
narcan 14 92.36 High High
anesthesia 12 90.20 High High
Neuropeptide 20 79.20 Quite High
Central nervous system 4 34.48 Quite Low
tolerance 1 31.12 Quite Low
agonist 4 24.16 Low Low
antagonist 21 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 3 100.00 Very High Very High Very High
Post Operative Pain 6 97.04 Very High Very High Very High
Myocardial Infarction 16 76.72 Quite High
Pressure Volume 2 Under Development 14 67.52 Quite High
Heart Rate Under Development 25 58.08 Quite High
Hyponatremia 62 50.00 Quite Low
Premature Birth 2 31.48 Quite Low
Nicotine Addiction 1 21.16 Low Low
Pre-term Labor 2 15.56 Low Low
Pressure And Volume Under Development 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Influence of epidural fentanyl on stress-induced elevation of plasma vasopressin (ADH) after surgery.
Regulation (Influence) of Positive_regulation (elevation) of vasopressin in plasma associated with stress and epidural
1) Confidence 0.53 Published 1983 Journal Anesth. Analg. Section Title Doc Link 6869858 Disease Relevance 0.36 Pain Relevance 0.82
To establish whether ethanol and/or endogenous opioids play a role in the control of arginine-vasopressin (AVP) response to physical exercise, six healthy men underwent six bicycle-ergometer tests until exhaustion [exercise control test; exercise plus ethanol (50 of 110 ml proof whiskey orally), exercise plus naloxone (2 mg injected plus 5 mg infused or 4 mg injected plus 10 mg infused intravenously] or exercise plus ethanol plus naloxone).
Spec (whether) Regulation (control) of Spec (whether) Positive_regulation (response) of arginine-vasopressin associated with narcan and endogenous opioid
2) Confidence 0.45 Published 2009 Journal J Neural Transm Section Abstract Doc Link 19649691 Disease Relevance 0 Pain Relevance 0.23
To establish whether ethanol and/or endogenous opioids play a role in the control of arginine-vasopressin (AVP) response to physical exercise, six healthy men underwent six bicycle-ergometer tests until exhaustion [exercise control test; exercise plus ethanol (50 of 110 ml proof whiskey orally), exercise plus naloxone (2 mg injected plus 5 mg infused or 4 mg injected plus 10 mg infused intravenously] or exercise plus ethanol plus naloxone).
Spec (whether) Regulation (control) of Spec (whether) Positive_regulation (response) of AVP associated with narcan and endogenous opioid
3) Confidence 0.45 Published 2009 Journal J Neural Transm Section Abstract Doc Link 19649691 Disease Relevance 0 Pain Relevance 0.23
Influence of epidural fentanyl on stress-induced elevation of plasma vasopressin (ADH) after surgery.
Regulation (Influence) of Positive_regulation (elevation) of ADH in plasma associated with stress and epidural
4) Confidence 0.45 Published 1983 Journal Anesth. Analg. Section Title Doc Link 6869858 Disease Relevance 0.36 Pain Relevance 0.83
With the exception of a slight increase in vasopressin level in the 40 mg/d treatment group, vasopressin levels in general, did not change significantly over the 12 hour study period.
Neg (not) Regulation (change) of Positive_regulation (increase) of vasopressin
5) Confidence 0.42 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2504060 Disease Relevance 0.13 Pain Relevance 0
A more likely explanation for the elevation of the fetal plasma AVP and OT is the facilitation by central cholinergic stimuli per se.
Regulation (facilitation) of Positive_regulation (elevation) of plasma AVP in plasma
6) Confidence 0.26 Published 2008 Journal BMC Dev Biol Section Body Doc Link PMC2570685 Disease Relevance 0.13 Pain Relevance 0.04

General Comments

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