INT46169

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Context Info
Confidence 0.67
First Reported 1983
Last Reported 2011
Negated 1
Speculated 0
Reported most in Body
Documents 14
Total Number 14
Disease Relevance 7.71
Pain Relevance 1.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
B19 1
IgG (Mus musculus)
Pain Link Frequency Relevance Heat
Migraine 4 97.10 Very High Very High Very High
ketamine 3 89.12 High High
Arthritis 25 85.00 Quite High
Inflammation 67 84.72 Quite High
Analgesic 2 83.36 Quite High
methotrexate 11 80.72 Quite High
cytokine 61 72.72 Quite High
chemokine 4 65.72 Quite High
cINOD 8 65.12 Quite High
rheumatoid arthritis 55 50.40 Quite High
Disease Link Frequency Relevance Heat
Influenza Virus Infection 96 100.00 Very High Very High Very High
Hypergammaglobulinemia 4 99.78 Very High Very High Very High
Immunization 78 99.32 Very High Very High Very High
Yersinia Infection 120 99.28 Very High Very High Very High
Targeted Disruption 46 98.90 Very High Very High Very High
Sprains And Strains 112 97.12 Very High Very High Very High
Headache 6 97.10 Very High Very High Very High
Flavivirus Infection 10 96.92 Very High Very High Very High
Disease 73 96.44 Very High Very High Very High
Shock 10 96.44 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Levels of IgG2 and IgG4 were undetectable in most people and when detected, were very low.
Transcription (Levels) of IgG
1) Confidence 0.67 Published 2006 Journal BMC Infect Dis Section Body Doc Link PMC1523344 Disease Relevance 0.55 Pain Relevance 0
No IgG(1) reaction was detected in any of the anti-sera tested.
Transcription (detected) of IgG
2) Confidence 0.48 Published 2007 Journal J Ethnopharmacol Section Abstract Doc Link 17141437 Disease Relevance 0.58 Pain Relevance 0.13
The appearance of PR8 influenza-specific serum IgG, BALF IgG, and BALF IgA responses was accelerated and significantly greater in the PCN-treated mice following influenza virus infection (Figure 6).
Transcription (appearance) of IgG associated with influenza virus infection
3) Confidence 0.32 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2743193 Disease Relevance 0.97 Pain Relevance 0
The appearance of PR8 influenza-specific serum IgG, BALF IgG, and BALF IgA responses was accelerated and significantly greater in the PCN-treated mice following influenza virus infection (Figure 6).
Transcription (appearance) of BALF IgG associated with influenza virus infection
4) Confidence 0.32 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2743193 Disease Relevance 0.97 Pain Relevance 0
BAFF Tg mice also had severe hypergammaglobulinemia with high levels of immunoglobulins, specifically IgG, IgM, IgA, and IgE isotypes; however, neither anti-SSA/Ro or anti-SSB/La autoantibodies were detected [79].
Transcription (levels) of IgG associated with targeted disruption and hypergammaglobulinemia
5) Confidence 0.25 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC3018660 Disease Relevance 1.71 Pain Relevance 0
Rituximab significantly reduced immunoglobulin production at the mRNA level, as well as total IgM and IgG content in synovia containing lymphoid aggregates, but not in synovia where lymphoid infiltration was diffuse.
Transcription (level) of IgG
6) Confidence 0.23 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2592782 Disease Relevance 0.05 Pain Relevance 0.03
133), and for the sera undetectable in IgG IIFT it was 1?
Transcription (undetectable) of IgG
7) Confidence 0.15 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2982812 Disease Relevance 0 Pain Relevance 0
Cross-reactive IgG antibodies were detected in 11 of 20 anti-JEV IgG positive sera.
Transcription (detected) of IgG
8) Confidence 0.12 Published 2010 Journal PLoS Neglected Tropical Diseases Section Body Doc Link PMC2982812 Disease Relevance 0.33 Pain Relevance 0
HBsAg specific IgA and IgG antibodies were detected in BAL samples obtained at the conclusion of the study (23 weeks after initial immunization) from mice immunized intranasally with HBsAg-NE (Figure 5A and B, respectively).
Transcription (detected) of IgG associated with immunization
9) Confidence 0.12 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2496893 Disease Relevance 0.24 Pain Relevance 0
The geometric mean levels for IgA, IgG, and IgM during the course of the study varied between 20–30?
Transcription (levels) of IgG
10) Confidence 0.06 Published 2010 Journal Clinical and Developmental Immunology Section Body Doc Link PMC3017893 Disease Relevance 0.31 Pain Relevance 0
Sera were tested for IgG at a starting dilution of 1?
Transcription (tested) of IgG
11) Confidence 0.05 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2726946 Disease Relevance 0.37 Pain Relevance 0.04
However, in mice the IgG titers were detected after the first immunization only in ELISA but not by the functional HAI assay with cRBC.
Neg (not) Transcription (detected) of IgG associated with immunization
12) Confidence 0.05 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2694350 Disease Relevance 0.57 Pain Relevance 0.23
In 54 patients with migraine and 70 persons comprising the control group, the total complement level (CH50) was evaluated together with its C3 and C4 fraction level and the level of IgG, IgA and IgM immunoglobulins.
Transcription (level) of IgG associated with migraine
13) Confidence 0.04 Published 1983 Journal Cephalalgia Section Abstract Doc Link 6871986 Disease Relevance 0.25 Pain Relevance 0.30
Parvovirus B19-specific IgG and IgM antibodies were initially detected 4 months after the onset of symptoms and remained detectable during the whole observation time.
Transcription (detected) of IgG in B19
14) Confidence 0.03 Published 2004 Journal Arthritis Res Ther Section Body Doc Link PMC400408 Disease Relevance 0.80 Pain Relevance 0.28

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