INT46271

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Context Info
Confidence 0.29
First Reported 1982
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (MAPKAP1) cytoplasmic membrane-bounded vesicle (MAPKAP1) plasma membrane (MAPKAP1)
nucleus (MAPKAP1) biological_process (MAPKAP1) response to stress (MAPKAP1)
MAPKAP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Potency 1 80.08 Quite High
tetrodotoxin 1 68.40 Quite High
Angina 2 40.88 Quite Low
agonist 13 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertension 4 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Thrombosis 3 5.00 Very Low Very Low Very Low
Stress 3 5.00 Very Low Very Low Very Low
Atherosclerosis 3 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Cv General 3 Under Development 2 5.00 Very Low Very Low Very Low
Myocardial Infarction 2 5.00 Very Low Very Low Very Low
Coronary Artery Disease 1 5.00 Very Low Very Low Very Low
Muscular Spasm 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Rolipram also potentiated responses to SIN-1 and sodium nitroprusside.
Regulation (responses) of SIN-1
1) Confidence 0.29 Published 1994 Journal Am. J. Respir. Crit. Care Med. Section Abstract Doc Link 7952568 Disease Relevance 0 Pain Relevance 0.07
The IC50-values of SIN-1, which is the pharmacologically active biotransformation product of molsidomine, were about 1 mumol/l in the experimental models used.
Regulation (values) of SIN-1
2) Confidence 0.20 Published 1982 Journal Arzneimittelforschung Section Abstract Doc Link 6896278 Disease Relevance 0 Pain Relevance 0.04
We have previously established that while both prostacyclin analogues, such as Cicaprost, and NO-donors, such as SIN-1, were indeed capable of cross-desensitizing or impairing Gq/PLC?
Regulation (capable) of SIN-1
3) Confidence 0.07 Published 2008 Journal Cellular Signalling Section Body Doc Link PMC2681257 Disease Relevance 0 Pain Relevance 0

General Comments

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